"Gelsolin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 90-kDa protein produced by macrophages that severs ACTIN filaments and forms a cap on the newly exposed filament end. Gelsolin is activated by CALCIUM ions and participates in the assembly and disassembly of actin, thereby increasing the motility of some CELLS.
| Descriptor ID |
D018260
|
| MeSH Number(s) |
D05.750.078.730.350 D12.644.360.372.437 D12.776.157.125.412.437 D12.776.220.525.350 D12.776.476.387.437
|
| Concept/Terms |
Gelsolin- Gelsolin
- Gelsolin Protein
- Serum Actin Inhibitory Protein
|
Below are MeSH descriptors whose meaning is more general than "Gelsolin".
Below are MeSH descriptors whose meaning is more specific than "Gelsolin".
This graph shows the total number of publications written about "Gelsolin" by people in this website by year, and whether "Gelsolin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 2 | 0 | 2 |
| 2007 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Gelsolin" by people in Profiles.
-
Raju R, Dalakas MC. Absence of upregulated genes associated with protein accumulations in desmin myopathy. Muscle Nerve. 2007 Mar; 35(3):386-8.
-
Christofidou-Solomidou M, Scherpereel A, Solomides CC, Muzykantov VR, Machtay M, Albelda SM, DiNubile MJ. Changes in plasma gelsolin concentration during acute oxidant lung injury in mice. Lung. 2002; 180(2):91-104.
-
Christofidou-Solomidou M, Scherpereel A, Solomides CC, Christie JD, Stossel TP, Goelz S, DiNubile MJ. Recombinant plasma gelsolin diminishes the acute inflammatory response to hyperoxia in mice. J Investig Med. 2002 Jan; 50(1):54-60.
-
Prendergast GC, Ziff EB. Mbh 1: a novel gelsolin/severin-related protein which binds actin in vitro and exhibits nuclear localization in vivo. EMBO J. 1991 Apr; 10(4):757-66.
-
Philp NJ, Nachmias VT. Components of the cytoskeleton in the retinal pigmented epithelium of the chick. J Cell Biol. 1985 Aug; 101(2):358-62.