Receptors, Adrenergic, beta-1
"Receptors, Adrenergic, beta-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-1 receptors are equally sensitive to EPINEPHRINE and NOREPINEPHRINE and bind the agonist DOBUTAMINE and the antagonist METOPROLOL with high affinity. They are found in the HEART, juxtaglomerular cells, and in the central and peripheral nervous systems.
| Descriptor ID |
D018342
|
| MeSH Number(s) |
D12.776.543.750.670.300.300.340.100 D12.776.543.750.695.150.300.340.700 D12.776.543.750.720.330.300.340.100
|
| Concept/Terms |
Receptors, Adrenergic, beta-1- Receptors, Adrenergic, beta-1
- Receptor, Adrenergic, beta-1
- Receptors, beta-1 Adrenergic
- Receptors, beta 1 Adrenergic
- beta-1 Adrenergic Receptors
- Adrenergic Receptors, beta-1
- beta 1 Adrenergic Receptors
- Adrenergic beta-1 Receptors
- Adrenergic beta 1 Receptors
- Receptors, Adrenergic beta-1
- beta-1 Receptors, Adrenergic
- Adrenergic Receptor, beta-1
- Adrenergic Receptor, beta 1
- Receptor, beta-1 Adrenergic
- beta-1 Adrenergic Receptor
- beta 1 Adrenergic Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, beta-1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Catecholamine [D12.776.543.750.670.300]
- Receptors, Adrenergic [D12.776.543.750.670.300.300]
- Receptors, Adrenergic, beta [D12.776.543.750.670.300.300.340]
- Receptors, Adrenergic, beta-1 [D12.776.543.750.670.300.300.340.100]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Catecholamine [D12.776.543.750.695.150]
- Receptors, Adrenergic [D12.776.543.750.695.150.300]
- Receptors, Adrenergic, beta [D12.776.543.750.695.150.300.340]
- Receptors, Adrenergic, beta-1 [D12.776.543.750.695.150.300.340.700]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Adrenergic [D12.776.543.750.720.330.300]
- Receptors, Adrenergic, beta [D12.776.543.750.720.330.300.340]
- Receptors, Adrenergic, beta-1 [D12.776.543.750.720.330.300.340.100]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, beta-1".
This graph shows the total number of publications written about "Receptors, Adrenergic, beta-1" by people in this website by year, and whether "Receptors, Adrenergic, beta-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 3 | 1 | 4 |
| 2008 | 3 | 2 | 5 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Adrenergic, beta-1" by people in Profiles.
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Yoo SM, Bhardwaj A, Benovic JL. Arresting Developments in Biased Signaling. Trends Pharmacol Sci. 2020 06; 41(6):387-389.
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Du Y, Li X, Yu H, Yan L, Lau WB, Zhang S, Qin Y, Wang W, Ma X, Liu H, Fu M. Activation of T Lymphocytes as a Novel Mechanism in Beta1-Adrenergic Receptor Autoantibody-Induced Cardiac Remodeling. Cardiovasc Drugs Ther. 2019 04; 33(2):149-161.
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Parikh KS, Fiuzat M, Davis G, Neely M, Blain-Nelson P, Whellan DJ, Abraham WT, Adams KF, Felker GM, Liggett SB, O'Connor CM, Bristow MR. Dose Response of ?-Blockers in Adrenergic Receptor Polymorphism Genotypes. Circ Genom Precis Med. 2018 08; 11(8):e002210.
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Irannejad R, Pessino V, Mika D, Huang B, Wedegaertner PB, Conti M, von Zastrow M. Functional selectivity of GPCR-directed drug action through location bias. Nat Chem Biol. 2017 Jul; 13(7):799-806.
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O-Uchi J, Komukai K, Kusakari Y, Morimoto S, Kawai M, Jhun BS, Hurst S, Hongo K, Sheu SS, Kurihara S. Alpha1-adrenenoceptor stimulation inhibits cardiac excitation-contraction coupling through tyrosine phosphorylation of beta1-adrenoceptor. Biochem Biophys Res Commun. 2013 Apr 05; 433(2):188-93.
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Fiuzat M, Neely ML, Starr AZ, Kraus WE, Felker GM, Donahue M, Adams K, Pi?a IL, Whellan D, O'Connor CM. Association between adrenergic receptor genotypes and beta-blocker dose in heart failure patients: analysis from the HF-ACTION DNA substudy. Eur J Heart Fail. 2013 Mar; 15(3):258-66.
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Seqqat R, Guo X, Rafiq K, Kolpakov MA, Guo J, Koch WJ, Houser SR, Dell'italia LJ, Sabri A. Beta1-adrenergic receptors promote focal adhesion signaling downregulation and myocyte apoptosis in acute volume overload. J Mol Cell Cardiol. 2012 Aug; 53(2):240-9.
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Carvalho AF, Mackie K, Van Bockstaele EJ. Cannabinoid modulation of limbic forebrain noradrenergic circuitry. Eur J Neurosci. 2010 Jan; 31(2):286-301.
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Reyes BA, Rosario JC, Piana PM, Van Bockstaele EJ. Cannabinoid modulation of cortical adrenergic receptors and transporters. J Neurosci Res. 2009 Dec; 87(16):3671-8.
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Fain JN, Cheema P, Tichansky DS, Madan AK. Stimulation of human omental adipose tissue lipolysis by growth hormone plus dexamethasone. Mol Cell Endocrinol. 2008 Nov 25; 295(1-2):101-5.