"Codon, Initiator" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A codon that directs initiation of protein translation (TRANSLATION, GENETIC) by stimulating the binding of initiator tRNA (RNA, TRANSFER, MET). In prokaryotes, the codons AUG or GUG can act as initiators while in eukaryotes, AUG is the only initiator codon.
| Descriptor ID |
D018387
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| MeSH Number(s) |
D13.444.735.544.355.225 G05.360.335.355.225 G05.360.340.024.340.137.190.225
|
| Concept/Terms |
Codon, Initiator- Codon, Initiator
- Codons, Initiator
- Initiator Codons
- Initiator Codon
- Start Codon
- Codon, Start
- Codons, Start
- Start Codons
- Codon, Initiation
- Codons, Initiation
- Initiation Codon
- Initiation Codons
|
Below are MeSH descriptors whose meaning is more general than "Codon, Initiator".
Below are MeSH descriptors whose meaning is more specific than "Codon, Initiator".
This graph shows the total number of publications written about "Codon, Initiator" by people in this website by year, and whether "Codon, Initiator" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Codon, Initiator" by people in Profiles.
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Shapiro JR, Lietman C, Grover M, Lu JT, Nagamani SC, Dawson BC, Baldridge DM, Bainbridge MN, Cohn DH, Blazo M, Roberts TT, Brennen FS, Wu Y, Gibbs RA, Melvin P, Campeau PM, Lee BH. Phenotypic variability of osteogenesis imperfecta type V caused by an IFITM5 mutation. J Bone Miner Res. 2013 Jul; 28(7):1523-30.
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Kim DY, Neely KA, Sassani JW, Vrabec TR, Tantri A, Frost A, Donoso LA. X-linked retinoschisis: novel mutation in the initiation codon of the XLRS1 gene in a large family. Retina. 2006 Oct; 26(8):940-6.
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Ma K, Temiakov D, Anikin M, McAllister WT. Probing conformational changes in T7 RNA polymerase during initiation and termination by using engineered disulfide linkages. Proc Natl Acad Sci U S A. 2005 Dec 06; 102(49):17612-7.
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Shibuya T, Rigoutsos I. Dictionary-driven prokaryotic gene finding. Nucleic Acids Res. 2002 Jun 15; 30(12):2710-25.
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Luzi P, Victoria T, Rafi MA, Wenger DA. Analysis of the 5' flanking region of the human galactocerebrosidase (GALC) gene. Biochem Mol Med. 1997 Dec; 62(2):159-64.