RNA, Messenger

"RNA, Messenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Descriptor ID	D012333
MeSH Number(s)	D13.444.735.544
Concept/Terms	RNA, Messenger RNA, Messenger mRNA Messenger RNA RNA, Polyadenylated RNA, Polyadenylated Polyadenylated RNA Poly(A) RNA Poly(A)+ RNA Poly(A) Tail Poly(A) Tail mRNA, Non-Polyadenylated mRNA, Non-Polyadenylated mRNA, Non Polyadenylated Non-Polyadenylated mRNA Non Polyadenylated mRNA mRNA, Polyadenylated mRNA, Polyadenylated RNA, Messenger, Polyadenylated Messenger RNA, Polyadenylated Polyadenylated Messenger RNA RNA, Polyadenylated Messenger Polyadenylated mRNA Poly(A)+ mRNA

Below are MeSH descriptors whose meaning is more general than "RNA, Messenger".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
RNA [D13.444.735]
RNA, Messenger [D13.444.735.544]

Below are MeSH descriptors whose meaning is related to "RNA, Messenger".

Below are MeSH descriptors whose meaning is more specific than "RNA, Messenger".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "RNA, Messenger" by people in this website by year, and whether "RNA, Messenger" was a major or minor topic of these publications.

Bar chart showing 653 publications over 29 distinct years, with a maximum of 46 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	21	22
1997	1	23	24
1998	6	16	22
1999	5	25	30
2000	4	24	28
2001	1	20	21
2002	4	35	39
2003	3	31	34
2004	5	20	25
2005	6	37	43
2006	5	41	46
2007	6	20	26
2008	5	26	31
2009	1	34	35
2010	4	20	24
2011	6	24	30
2012	4	20	24
2013	9	21	30
2014	7	20	27
2015	4	18	22
2016	6	7	13
2017	4	7	11
2018	3	4	7
2019	1	9	10
2020	4	4	8
2021	2	4	6
2022	0	10	10
2023	0	2	2
2024	2	1	3

Below are the most recent publications written about "RNA, Messenger" by people in Profiles.

Xue L, Zhao G, Gong N, Han X, Shepherd SJ, Xiong X, Xiao Z, Palanki R, Xu J, Swingle KL, Warzecha CC, El-Mayta R, Chowdhary V, Yoon IC, Xu J, Cui J, Shi Y, Alameh MG, Wang K, Wang L, Pochan DJ, Weissman D, Vaughan AE, Wilson JM, Mitchell MJ. Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery. Nat Nanotechnol. 2025 Jan; 20(1):132-143.

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Vukovic I, Barnada SM, Ruffin JW, Karlin J, Lokareddy RK, Cingolani G, McMahon SB. Non-redundant roles for the human mRNA decapping cofactor paralogs DCP1a and DCP1b. Life Sci Alliance. 2024 11; 7(11).

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Lazarevic B, Casola AR, Chambers CV. COVID-19 mRNA Vaccination Trends Among Immunocompromised Patients. J Am Board Fam Med. 2024 01 05; 36(6):927-932.

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Qin J, Jeon JH, Xu J, Langston LK, Marasini R, Mou S, Montoya B, Melo-Silva CR, Jeon HJ, Zhu T, Sigal LJ, Xu R, Zhu H. Design and preclinical evaluation of a universal SARS-CoV-2 mRNA vaccine. Front Immunol. 2023; 14:1126392.

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Beyoglu D, Schwalm S, Semmo N, Huwiler A, Idle JR. Hepatitis C Virus Infection Upregulates Plasma Phosphosphingolipids and Endocannabinoids and Downregulates Lysophosphoinositols. Int J Mol Sci. 2023 01 11; 24(2).

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Kocher F, Puccini A, Untergasser G, Martowicz A, Zimmer K, Pircher A, Baca Y, Xiu J, Haybaeck J, Tymoszuk P, Goldberg RM, Petrillo A, Shields AF, Salem ME, Marshall JL, Hall M, Korn WM, Nabhan C, Battaglin F, Lenz HJ, Lou E, Choo SP, Toh CK, Gasteiger S, Pichler R, Wolf D, Seeber A. Multi-omic Characterization of Pancreatic Ductal Adenocarcinoma Relates CXCR4 mRNA Expression Levels to Potential Clinical Targets. Clin Cancer Res. 2022 11 14; 28(22):4957-4967.

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Valentine H, Aiken W, Morrison B, Zhao Z, Fowle H, Wasserman JS, Thompson E, Chin W, Young M, Clarke S, Gibbs D, Harrison S, McLaughlin W, Kwok T, Jin F, Campbell KS, Horvath A, Thompson R, Lee NH, Zhou Y, Gra?a X, Ragin C, Badal S. Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient. Cancer Res Commun. 2022 11; 2(11):1355-1371.

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Mucha B, Qie S, Bajpai S, Tarallo V, Diehl JN, Tedeschi F, Zhou G, Gao Z, Flashner S, Klein-Szanto AJ, Hibshoosh H, Masataka S, Chajewski OS, Majsterek I, Pytel D, Hatzoglou M, Der CJ, Nakagawa H, Bass AJ, Wong KK, Fuchs SY, Rustgi AK, Jankowsky E, Diehl JA. Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation. Nat Commun. 2022 11 03; 13(1):6614.

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Kuttiyatveetil JRA, Soufari H, Dasovich M, Uribe IR, Mirhasan M, Cheng SJ, Leung AKL, Pascal JM. Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a distinctive mode of engaging poly(ADP-ribose). Cell Rep. 2022 10 25; 41(4):111529.

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Britto C, Mohorianu I, Yeung T, Cheung E, Novak T, Hall MW, Mourani PM, Weiss SL, Thomas NJ, Markovitz B, Randolph AG, Moffitt KL. Host Respiratory Transcriptome Signature Associated with Poor Outcome in Children with Influenza-Staphylococcus aureus Pneumonia. J Infect Dis. 2022 09 28; 226(7):1286-1294.

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