"Mucin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.
| Descriptor ID |
D018396
|
| MeSH Number(s) |
D12.776.395.550.560 D12.776.395.560.631.115 D12.776.543.550.530 D23.050.285.050.300 D23.050.550.325.300 D23.101.140.075.300
|
| Concept/Terms |
Mucin-1- Mucin-1
- Mucin 1
- CA 15.3 Antigen
- Antigen, CA 15.3
- Antigen CA-15-3
- Antigen CA 15 3
- CA-15-3, Antigen
- CA-15-3 Antigen
- Antigen, CA-15-3
- Episialin
- CD227 Antigen
- Antigen, CD227
- Polymorphic Epithelial Mucin
- Epithelial Membrane Antigen
- Antigen, Epithelial Membrane
- Membrane Antigen, Epithelial
- Muc1 Mucin
- Mucin, Muc1
- Antigens, CD227
- CD227 Antigens
- CA 15-3 Antigen
- Antigen, CA 15-3
- CA 15 3 Antigen
- Epithelial Mucin, Polymorphic
- Mucin, Polymorphic Epithelial
|
Below are MeSH descriptors whose meaning is more general than "Mucin-1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Glycoproteins [D12.776.395]
- Membrane Glycoproteins [D12.776.395.550]
- Mucin-1 [D12.776.395.550.560]
- Mucoproteins [D12.776.395.560]
- Mucins [D12.776.395.560.631]
- Mucin-1 [D12.776.395.560.631.115]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Mucin-1 [D12.776.543.550.530]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Neoplasm [D23.050.285]
- Antigens, Tumor-Associated, Carbohydrate [D23.050.285.050]
- Mucin-1 [D23.050.285.050.300]
- Epitopes [D23.050.550]
- Antigens, Tumor-Associated, Carbohydrate [D23.050.550.325]
- Mucin-1 [D23.050.550.325.300]
- Biomarkers [D23.101]
- Biomarkers, Tumor [D23.101.140]
- Antigens, Tumor-Associated, Carbohydrate [D23.101.140.075]
- Mucin-1 [D23.101.140.075.300]
Below are MeSH descriptors whose meaning is more specific than "Mucin-1".
This graph shows the total number of publications written about "Mucin-1" by people in this website by year, and whether "Mucin-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Mucin-1" by people in Profiles.
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Kato K, Zemskova MA, Hanss AD, Kim MM, Summer R, Kim KC. Muc1 deficiency exacerbates pulmonary fibrosis in a mouse model of silicosis. Biochem Biophys Res Commun. 2017 11 25; 493(3):1230-1235.
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Eminaga O, Wei W, Hawley SJ, Auman H, Newcomb LF, Simko J, Hurtado-Coll A, Troyer DA, Carroll PR, Gleave ME, Lin DW, Nelson PS, Thompson IM, True LD, McKenney JK, Feng Z, Fazli L, Brooks JD. MUC1 Expression by Immunohistochemistry Is Associated with Adverse Pathologic Features in Prostate Cancer: A Multi-Institutional Study. PLoS One. 2016; 11(11):e0165236.
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Huang Y, Zimmerman RL, Bibbo M. Diagnostic value of CA 15-3 antibody in detecting metastatic adenocarcinoma. Anal Quant Cytol Histol. 2004 Oct; 26(5):259-62.
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Resetkova E, Gonzalez-Angulo AM, Sneige N, Mcdonnell TJ, Buzdar AU, Kau SW, Yamamura Y, Reuben JM, Hortobagyi GN, Cristofanilli M. Prognostic value of P53, MDM-2, and MUC-1 for patients with inflammatory breast carcinoma. Cancer. 2004 Sep 1; 101(5):913-7.
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Zimmerman RL, Burke M, Young NA, Solomides CC, Bibbo M. Diagnostic utility of Glut-1 and CA 15-3 in discriminating adenocarcinoma from hepatocellular carcinoma in liver tumors biopsied by fine-needle aspiration. Cancer. 2002 Feb 25; 96(1):53-7.
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Dizon MA, Multhaupt HA, Paskin DL, Warhol MJ. Osteoclastic giant cell tumor of the pancreas: an immunohistochemical study. Arch Pathol Lab Med. 1996 Mar; 120(3):306-9.