Disease Progression

"Disease Progression" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.

Descriptor ID	D018450
MeSH Number(s)	C23.550.291.656
Concept/Terms	Disease Progression Disease Progression Disease Progressions Progression, Disease Progressions, Disease Disease Exacerbation Disease Exacerbation

Below are MeSH descriptors whose meaning is more general than "Disease Progression".

Diseases [C]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Disease Attributes [C23.550.291]
Disease Progression [C23.550.291.656]

Below are MeSH descriptors whose meaning is related to "Disease Progression".

Below are MeSH descriptors whose meaning is more specific than "Disease Progression".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Disease Progression" by people in this website by year, and whether "Disease Progression" was a major or minor topic of these publications.

Bar chart showing 1469 publications over 30 distinct years, with a maximum of 83 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	7	7
1997	0	22	22
1998	0	17	17
1999	0	17	17
2000	0	29	29
2001	0	20	20
2002	0	28	28
2003	0	46	46
2004	0	48	48
2005	0	56	56
2006	0	49	49
2007	0	76	76
2008	0	59	59
2009	3	53	56
2010	5	73	78
2011	6	70	76
2012	2	71	73
2013	3	64	67
2014	1	70	71
2015	9	71	80
2016	4	72	76
2017	2	81	83
2018	3	68	71
2019	1	76	77
2020	4	61	65
2021	3	32	35
2022	0	26	26
2023	0	21	21
2024	9	29	38
2025	0	2	2

Below are the most recent publications written about "Disease Progression" by people in Profiles.

Hayes D, Jennerich AL, Coleman RD, Abston E, Adamson GT, Berger JT, Cohen SP, Cooper DS, Eghtesady P, Fynn-Thompson F, Grady RM, Hon SM, Hoopes CW, Jewell T, Lewthwaite H, Liu MF, McGiffin DC, Mullen MP, Qureshi AM, Morales DLS. Interventional Strategies for Children with Progressive Pulmonary Hypertension Despite Optimal Therapy: An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med. 2025 Feb; 211(2):157-173.

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Odisio BC, Wah TM, Fotiadis N, Anton K, Yoon CJ, Stanziola J, Mamun A, Meyers EE, De Leon H. Safety and Effectiveness of Microwave Ablation of Liver Tumors: Initial Real-World Results from the Multinational NeuWave Observational Liver Ablation (NOLA) Registry. J Vasc Interv Radiol. 2025 05; 36(5):813-822.e5.

View in: PubMed
Jiang C, Li Y, Duan K, Zhan T, Chen Z, Wang Y, Zhao R, Ma C, Guo Y, Liu C. [Parkin deletion affects PINK1/Parkin-mediated mitochondrial autophagy to exacerbate neuroinflammation and accelerate progression of Parkinson's disease in mice]. Nan Fang Yi Ke Da Xue Xue Bao. 2024 Dec 20; 44(12):2359-2366.

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Giovannoni G, Boyko A, Correale J, Edan G, Freedman MS, Montalban X, Rammohan K, Stefoski D, Yamout B, Leist T, Aydemir A, Borsi L, Verdun di Cantogno E. Long-term follow-up of patients with a first clinical demyelinating event (clinically isolated syndrome) who received cladribine tablets in CLASSIC-MS: Findings for the ORACLE-MS cohort. Mult Scler. 2025 Jan; 31(1):44-58.

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Salisbury ML, Markin C, Fadely T, Guttentag AR, Humphries SM, Lynch DA, Kropski JA, Blackwell TS. Progressive Early Interstitial Lung Abnormalities in Persons at Risk for Familial Pulmonary Fibrosis: A Prospective Cohort Study. Am J Respir Crit Care Med. 2024 Dec 15; 210(12):1441-1452.

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Alshaikhsalama AM, Alsoudi AF, Wai KM, Koo E, Mruthyunjaya P, Rahimy E. Association between Obstructive Sleep Apnea and Age-related Macular Degeneration Development and Progression. Ophthalmol Retina. 2025 Jun; 9(6):537-545.

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Alsoudi AF, Wai KM, Koo E, Mruthyunjaya P, Rahimy E. Curcuma-Based Nutritional Supplements and Risk of Age-Related Macular Degeneration. JAMA Ophthalmol. 2024 Dec 01; 142(12):1114-1121.

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Perry NJ, Wang S, Smith R, Duffy R, Queenan M, Perman MJ, Lerman MA, Larijani M. Rapidly Progressive Idiopathic Pyoderma Gangrenosum in a Pediatric Patient Successfully Treated With Infliximab. Pediatr Dermatol. 2025 May-Jun; 42(3):603-607.

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Skolnik N, Yawn BP, Correia de Sousa J, V?zquez MMM, Barnard A, Wright WL, Ulrich A, Winders T, Brunton S. Best practice advice for asthma exacerbation prevention and management in primary care: an international expert consensus. NPJ Prim Care Respir Med. 2024 Nov 17; 34(1):39.

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G?mez LF, Kinnee E, Kaufman JD, Young MT, Fitzpatrick AM, Phipatanakul W, Mauger DT, McClure LA, Bilal U, Holguin F, Clougherty JE. Modification of asthma treatment efficacy by healthcare access: A reanalysis of AsthmaNet Step-Up Yellow Zone Inhaled Corticosteroids to Prevent Exacerbations (STICS) clinical trial. Respir Med. 2024 Nov-Dec; 234:107853.

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