Spectrometry, Mass, Secondary Ion
"Spectrometry, Mass, Secondary Ion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass-spectrometric technique that is used for microscopic chemical analysis. A beam of primary ions with an energy of 5-20 kiloelectronvolts (keV) bombards a small spot on the surface of the sample under ultra-high vacuum conditions. Positive and negative secondary ions sputtered from the surface are analyzed in a mass spectrometer in regards to their mass-to-charge ratio. Digital imaging can be generated from the secondary ion beams and their intensity can be measured. Ionic images can be correlated with images from light or other microscopy providing useful tools in the study of molecular and drug actions.
Descriptor ID |
D018629
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MeSH Number(s) |
E05.196.566.760
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Concept/Terms |
Spectrometry, Mass, Secondary Ion- Spectrometry, Mass, Secondary Ion
- Secondary Ion Mass Spectroscopy Microscopy
- Mass Spectrometry, Secondary Ion
- Secondary Ion Mass Spectrometry
- SIMS Microscopy
- Secondary Ion Mass Spectroscopy
- Mass Spectroscopy, Secondary Ion
- Spectroscopy, Mass, Secondary Ion
- Secondary Ion Mass Spectrometry Microscopy
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Below are MeSH descriptors whose meaning is more general than "Spectrometry, Mass, Secondary Ion".
Below are MeSH descriptors whose meaning is more specific than "Spectrometry, Mass, Secondary Ion".
This graph shows the total number of publications written about "Spectrometry, Mass, Secondary Ion" by people in this website by year, and whether "Spectrometry, Mass, Secondary Ion" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Spectrometry, Mass, Secondary Ion" by people in Profiles.
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Marchany MD, Gardella JA, Kuchera TJ. Time of flight secondary ion mass spectrometry surface and in-depth study of degradation of nanosheet poly(L-lactic acid) films. Biointerphases. 2015 Mar 20; 10(1):019010.
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Theilacker WM, Bui H, Beebe TP. Optimization of protein patterns for neuronal cell culture applications. Biointerphases. 2011 Sep; 6(3):105.
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Quong JN, Quong AA, Wu KJ, Kercher JR. A signature-based method to distinguish time-of-flight secondary-ion mass spectra from biological samples. Chem Biodivers. 2005 Nov; 2(11):1495-502.