Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.
| Descriptor ID |
D019032
|
| MeSH Number(s) |
E05.196.566.755
|
| Concept/Terms |
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectrometry, Matrix Assisted Laser Desorption Ionization
- Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
- Matrix Assisted Laser Desorption Ionization Mass Spectrometry
- MALDI
- Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization
- MS-MALD
- MALD-MS
- MALDI-MS
- MALDI MS
- Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted
- Laser Desorption Ionization Mass Spectrometry, Matrix Assisted
- Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectroscopy, Matrix Assisted Laser Desorption Ionization
|
Below are MeSH descriptors whose meaning is more general than "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".
Below are MeSH descriptors whose meaning is more specific than "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".
This graph shows the total number of publications written about "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" by people in this website by year, and whether "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 8 | 8 |
| 2003 | 1 | 6 | 7 |
| 2004 | 0 | 5 | 5 |
| 2005 | 0 | 6 | 6 |
| 2006 | 1 | 7 | 8 |
| 2007 | 0 | 3 | 3 |
| 2008 | 0 | 7 | 7 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 6 | 6 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 4 | 4 |
| 2016 | 2 | 1 | 3 |
| 2017 | 0 | 3 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" by people in Profiles.
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Choe K, Jindra MA, Hubbard SC, Pfleger BF, Sweedler JV. MALDI-MS screening of microbial colonies with isomer resolution to select fatty acid desaturase variants. Anal Biochem. 2023 07 01; 672:115169.
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Lee JW, Lee K, Ahn SH, Son BH, Ko BS, Kim HJ, Chung IY, Kim J, Lee W, Ko MS, Choi S, Chang S, Ko CK, Lee SB, Kim DC. Potential of MALDI-TOF-based serum N-glycan analysis for the diagnosis and surveillance of breast cancer. Sci Rep. 2020 11 05; 10(1):19136.
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Lee SB, Bose S, Ahn SH, Son BH, Ko BS, Kim HJ, Chung IY, Kim J, Lee W, Ko MS, Lee K, Chang S, Park HS, Lee JW, Kim DC. Breast cancer diagnosis by analysis of serum N-glycans using MALDI-TOF mass spectroscopy. PLoS One. 2020; 15(4):e0231004.
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Brown-Elliott BA, Fritsche TR, Olson BJ, Vasireddy S, Vasireddy R, Iakhiaeva E, Alame D, Wallace RJ, Branda JA. Comparison of Two Commercial Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) Systems for Identification of Nontuberculous Mycobacteria. Am J Clin Pathol. 2019 09 09; 152(4):527-536.
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Gorre E, Muste C, Owens KG. Introducing a Cell-Free Approach for the Identification of Brewing Yeast (Saccharomyces cerevisiae) Strains Using MALDI-TOF MS. J Am Soc Mass Spectrom. 2018 Nov; 29(11):2248-2259.
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Leijon H, Kaprio T, Heiskanen A, Satomaa T, Hiltunen JO, Miettinen MM, Arola J, Haglund C. N-Glycomic Profiling of Pheochromocytomas and Paragangliomas Separates Metastatic and Nonmetastatic Disease. J Clin Endocrinol Metab. 2017 11 01; 102(11):3990-4000.
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Gomez EJ, Roberts AL, Robinson DP, Alby K, Ledeboer NA, Doern CD, Lander DW, Bearman G, Sullivan KV. Impact of Organism Identification Method on Central Line-Associated Bloodstream Infection Designation. Infect Control Hosp Epidemiol. 2017 08; 38(8):1007-1009.
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Bennuru S, Lustigman S, Abraham D, Nutman TB. Metabolite profiling of infection-associated metabolic markers of onchocerciasis. Mol Biochem Parasitol. 2017 07; 215:58-69.
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Karlowsky JA, Biedenbach DJ, Bouchillon SK, Hackel M, Iaconis JP, Sahm DF. In vitro activity of Ceftaroline against bacterial pathogens isolated from patients with skin and soft tissue and respiratory tract infections in African and Middle Eastern countries: AWARE global surveillance program 2012-2014. Diagn Microbiol Infect Dis. 2016 Oct; 86(2):194-9.
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Hoang K, Pophristic M, Horan AJ, Johnston MV, McEwen CN. High Sensitivity Analysis of Nanoliter Volumes of Volatile and Nonvolatile Compounds using Matrix Assisted Ionization (MAI) Mass Spectrometry. J Am Soc Mass Spectrom. 2016 10; 27(10):1590-6.