Caco-2 Cells

"Caco-2 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells, such as ENTEROCYTES. These cells are valuable in vitro tools for studies related to intestinal cell function and differentiation.

Descriptor ID	D018938
MeSH Number(s)	A11.251.210.190.160 A11.251.860.180.160 A11.436.140
Concept/Terms	Caco-2 Cells Caco-2 Cells Caco 2 Cells Caco-2 Cell Cell, Caco-2 Cells, Caco-2

Below are MeSH descriptors whose meaning is more general than "Caco-2 Cells".

Anatomy [A]
Cells [A11]
Cells, Cultured [A11.251]
Cell Line [A11.251.210]
Cell Line, Tumor [A11.251.210.190]
Caco-2 Cells [A11.251.210.190.160]
Tumor Cells, Cultured [A11.251.860]
Cell Line, Tumor [A11.251.860.180]
Caco-2 Cells [A11.251.860.180.160]
Epithelial Cells [A11.436]
Caco-2 Cells [A11.436.140]

Below are MeSH descriptors whose meaning is related to "Caco-2 Cells".

Below are MeSH descriptors whose meaning is more specific than "Caco-2 Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Caco-2 Cells" by people in this website by year, and whether "Caco-2 Cells" was a major or minor topic of these publications.

Bar chart showing 14 publications over 9 distinct years, with a maximum of 3 publications in 2013

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2002	1	1
2004	2	2
2005	1	1
2006	2	2
2007	1	1
2009	1	1
2012	2	2
2013	3	3
2017	1	1

Below are the most recent publications written about "Caco-2 Cells" by people in Profiles.

Said AH, Hu S, Abutaleb A, Watkins T, Cheng K, Chahdi A, Kuppusamy P, Saxena N, Xie G, Raufman JP. Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells. Biochem J. 2017 Feb 20; 474(5):647-665.

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Chahdi A, Raufman JP. The Cdc42/Rac nucleotide exchange factor protein ß1Pix (Pak-interacting exchange factor) modulates ß-catenin transcriptional activity in colon cancer cells: evidence for direct interaction of ß1PIX with ß-catenin. J Biol Chem. 2013 Nov 22; 288(47):34019-29.

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Gauss A, Buchholz I, Zahn A, Schmitz G, Stremmel W, Fuellekrug J, Ehehalt R. Flotillin-2 expression in the human gut: from a cell model to human tissue in health and inflammatory bowel diseases. Int J Med Sci. 2013; 10(10):1259-70.

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Stec J, Fomovska A, Afanador GA, Muench SP, Zhou Y, Lai BS, El Bissati K, Hickman MR, Lee PJ, Leed SE, Auschwitz JM, Sommervile C, Woods S, Roberts CW, Rice D, Prigge ST, McLeod R, Kozikowski AP. Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii. ChemMedChem. 2013 Jul; 8(7):1138-60.

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Lin JE, Snook AE, Li P, Stoecker BA, Kim GW, Magee MS, Garcia AV, Valentino MA, Hyslop T, Schulz S, Waldman SA. GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity. PLoS One. 2012; 7(2):e31686.

View in: PubMed
Sheng XC, Appleby T, Butler T, Cai R, Chen X, Cho A, Clarke MO, Cottell J, Delaney WE, Doerffler E, Link J, Ji M, Pakdaman R, Pyun HJ, Wu Q, Xu J, Kim CU. Discovery of GS-9451: an acid inhibitor of the hepatitis C virus NS3/4A protease. Bioorg Med Chem Lett. 2012 Apr 01; 22(7):2629-34.

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Lubbe WJ, Zuzga DS, Zhou Z, Fu W, Pelta-Heller J, Muschel RJ, Waldman SA, Pitari GM. Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9. Cancer Res. 2009 Apr 15; 69(8):3529-36.

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Kolachala VL, Bajaj R, Wang L, Yan Y, Ritzenthaler JD, Gewirtz AT, Roman J, Merlin D, Sitaraman SV. Epithelial-derived fibronectin expression, signaling, and function in intestinal inflammation. J Biol Chem. 2007 Nov 09; 282(45):32965-73.

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Pitari GM, Li T, Baksh RI, Waldman SA. Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells. Mol Cancer Ther. 2006 May; 5(5):1190-6.

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Lubbe WJ, Zhou ZY, Fu W, Zuzga D, Schulz S, Fridman R, Muschel RJ, Waldman SA, Pitari GM. Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer. Clin Cancer Res. 2006 Mar 15; 12(6):1876-82.

View in: PubMed

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