"Selectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transmembrane proteins consisting of a lectin-like domain, an epidermal growth factor-like domain, and a variable number of domains that are homologous to complement regulatory proteins. They are important cell adhesion molecules which help LEUKOCYTES attach to VASCULAR ENDOTHELIUM.
| Descriptor ID |
D019087
|
| MeSH Number(s) |
D12.776.395.550.200.700 D12.776.503.843 D12.776.543.550.200.700 D23.050.301.350.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Selectins".
Below are MeSH descriptors whose meaning is more specific than "Selectins".
This graph shows the total number of publications written about "Selectins" by people in this website by year, and whether "Selectins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Selectins" by people in Profiles.
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Miles FL, Pruitt FL, van Golen KL, Cooper CR. Stepping out of the flow: capillary extravasation in cancer metastasis. Clin Exp Metastasis. 2008; 25(4):305-24.
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Schumacher G, Bakowsky U, Gege C, Schmidt RR, Rothe U, Bendas G. Lessons learned from clustering of fluorinated glycolipids on selectin ligand function in cell rolling. Biochemistry. 2006 Mar 7; 45(9):2894-903.
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Kretschmer U, Bonhagen K, Debes GF, Mittrücker HW, Erb KJ, Liesenfeld O, Zaiss D, Kamradt T, Syrbe U, Hamann A. Expression of selectin ligands on murine effector and IL-10-producing CD4+ T cells from non-infected and infected tissues. Eur J Immunol. 2004 Nov; 34(11):3070-81.
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Bakowsky U, Schumacher G, Gege C, Schmidt RR, Rothe U, Bendas G. Cooperation between lateral ligand mobility and accessibility for receptor recognition in selectin-induced cell rolling. Biochemistry. 2002 Apr 9; 41(14):4704-12.
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Aplin AE, Howe A, Alahari SK, Juliano RL. Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins. Pharmacol Rev. 1998 Jun; 50(2):197-263.