"Integrases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA.
Descriptor ID |
D019426
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MeSH Number(s) |
D08.811.739.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Integrases".
Below are MeSH descriptors whose meaning is more specific than "Integrases".
This graph shows the total number of publications written about "Integrases" by people in this website by year, and whether "Integrases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 2 | 2 |
2006 | 0 | 1 | 1 |
2008 | 1 | 1 | 2 |
2009 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 0 | 2 | 2 |
2012 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2017 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2020 | 0 | 1 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Integrases" by people in Profiles.
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Hamidi A, Wolf A, Dueva R, Kaufmann M, G?pelt K, Iliakis G, Metzen E. Depletion of HIF-1a by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in Hypoxia. Cells. 2022 05 18; 11(10).
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James CW, Szabo S, Kahal D, Goldstein ND. The effect of multivitamins and polyvalent cations on virologic suppression with integrase strand transfer inhibitors. AIDS. 2020 03 01; 34(3):487-489.
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Rhodes CT, Zunino G, Huang SA, Cardona SM, Cardona AE, Berger MS, Lemmon VP, Lin CA. Region specific knock-out reveals distinct roles of chromatin modifiers in adult neurogenic niches. Cell Cycle. 2018; 17(3):377-389.
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Zhao L, Thorsheim CL, Suzuki A, Stalker TJ, Min SH, Lian L, Fairn GD, Cockcroft S, Durham A, Krishnaswamy S, Abrams CS. Phosphatidylinositol transfer protein-a in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis. Nat Commun. 2017 10 31; 8(1):1216.
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Aiyer S, Rossi P, Malani N, Schneider WM, Chandar A, Bushman FD, Montelione GT, Roth MJ. Structural and sequencing analysis of local target DNA recognition by MLV integrase. Nucleic Acids Res. 2015 Jun 23; 43(11):5647-63.
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Shin S, Upadhyay N, Greenbaum LE, Kaestner KH. Ablation of Foxl1-Cre-labeled hepatic progenitor cells and their descendants impairs recovery of mice from liver injury. Gastroenterology. 2015 Jan; 148(1):192-202.e3.
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Hamilton KE, Noubissi FK, Katti PS, Hahn CM, Davey SR, Lundsmith ET, Klein-Szanto AJ, Rhim AD, Spiegelman VS, Rustgi AK. IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts. Carcinogenesis. 2013 Nov; 34(11):2647-54.
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Shen TH, Gladoun N, Castillo-Martin M, Bonal D, Domingo-Domenech J, Charytonowicz D, Cordon-Cardo C. A BAC-based transgenic mouse specifically expresses an inducible Cre in the urothelium. PLoS One. 2012; 7(4):e35243.
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Shin S, Walton G, Aoki R, Brondell K, Schug J, Fox A, Smirnova O, Dorrell C, Erker L, Chu AS, Wells RG, Grompe M, Greenbaum LE, Kaestner KH. Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential. Genes Dev. 2011 Jun 1; 25(11):1185-92.
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Hu T, Gimferrer I, Simmons A, Wiest D, Alberola-Ila J. The Ras/MAPK pathway is required for generation of iNKT cells. PLoS One. 2011 May 10; 6(5):e19890.