Dendritic Cells, Follicular
"Dendritic Cells, Follicular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-hematopoietic cells, with extensive dendritic processes, found in the primary and secondary follicles of lymphoid tissue (the B cell zones). They are different from conventional DENDRITIC CELLS associated with T-CELLS. They are derived from MESENCHYMAL STEM CELLS and are negative for class II MHC antigen and do not process or present antigen like the conventional dendritic cells do. Instead, follicular dendritic cells have FC RECEPTORS and C3B RECEPTORS that hold antigen in the form of ANTIGEN-ANTIBODY COMPLEXES on their surfaces for long periods for recognition by B-CELLS.
| Descriptor ID |
D020566
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| MeSH Number(s) |
A10.549.400.500.200 A11.066.275 A15.382.066.275 A15.382.520.604.412.500.200
|
| Concept/Terms |
Dendritic Cells, Follicular- Dendritic Cells, Follicular
- Dendritic Cell, Follicular
- Follicular Dendritic Cell
- Follicular Dendritic Cells
- Dendritic Reticulum Cells, Follicular
|
Below are MeSH descriptors whose meaning is more general than "Dendritic Cells, Follicular".
Below are MeSH descriptors whose meaning is more specific than "Dendritic Cells, Follicular".
This graph shows the total number of publications written about "Dendritic Cells, Follicular" by people in this website by year, and whether "Dendritic Cells, Follicular" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2007 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dendritic Cells, Follicular" by people in Profiles.
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Mattsson J, Yrlid U, Stensson A, Sch?n K, Karlsson MC, Ravetch JV, Lycke NY. Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant. J Immunol. 2011 Oct 01; 187(7):3641-52.
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Coffey F, Alabyev B, Manser T. Initial clonal expansion of germinal center B cells takes place at the perimeter of follicles. Immunity. 2009 Apr 17; 30(4):599-609.
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Rahman ZS, Niu H, Perry D, Wakeland E, Manser T, Morel L. Expression of the autoimmune Fcgr2b NZW allele fails to be upregulated in germinal center B cells and is associated with increased IgG production. Genes Immun. 2007 Oct; 8(7):604-12.
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Soriano AO, Thompson MA, Admirand JH, Fayad LE, Rodriguez AM, Romaguera JE, Hagemeister FB, Pro B. Follicular dendritic cell sarcoma: a report of 14 cases and a review of the literature. Am J Hematol. 2007 Aug; 82(8):725-8.
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Rahman ZS, Manser T. Failed up-regulation of the inhibitory IgG Fc receptor Fc gamma RIIB on germinal center B cells in autoimmune-prone mice is not associated with deletion polymorphisms in the promoter region of the Fc gamma RIIB gene. J Immunol. 2005 Aug 1; 175(3):1440-9.
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Wen L, Shinton SA, Hardy RR, Hayakawa K. Association of B-1 B cells with follicular dendritic cells in spleen. J Immunol. 2005 Jun 01; 174(11):6918-26.
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Rao SP, Vora KA, Manser T. Differential expression of the inhibitory IgG Fc receptor FcgammaRIIB on germinal center cells: implications for selection of high-affinity B cells. J Immunol. 2002 Aug 15; 169(4):1859-68.
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Qin D, Wu J, Vora KA, Ravetch JV, Szakal AK, Manser T, Tew JG. Fc gamma receptor IIB on follicular dendritic cells regulates the B cell recall response. J Immunol. 2000 Jun 15; 164(12):6268-75.