RNA Stability

"RNA Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The extent to which an RNA molecule retains its structural integrity and resists degradation by RNASE, and base-catalyzed HYDROLYSIS, under changing in vivo or in vitro conditions.

Descriptor ID	D020871
MeSH Number(s)	G02.111.780
Concept/Terms	RNA Stability RNA Stability Stability, RNA mRNA Stability mRNA Stability Stability, mRNA mRNA Degradation mRNA Degradation Degradation, mRNA mRNA Transcript Degradation Degradation, mRNA Transcript Transcript Degradation, mRNA RNA Degradation RNA Degradation Degradation, RNA RNA Instability RNA Instability Instability, RNA mRNA Decay mRNA Decay Decay, mRNA mRNA Instability mRNA Instability Instability, mRNA RNA Decay RNA Decay Decay, RNA

Below are MeSH descriptors whose meaning is more general than "RNA Stability".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
RNA Stability [G02.111.780]

Below are MeSH descriptors whose meaning is related to "RNA Stability".

Below are MeSH descriptors whose meaning is more specific than "RNA Stability".

RNA Stability
Nonsense Mediated mRNA Decay

publications

Timeline | Most Recent

This graph shows the total number of publications written about "RNA Stability" by people in this website by year, and whether "RNA Stability" was a major or minor topic of these publications.

Bar chart showing 22 publications over 17 distinct years, with a maximum of 3 publications in 2006 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2005	0	1	1
2006	0	3	3
2007	1	0	1
2008	0	2	2
2010	1	0	1
2011	0	1	1
2012	0	1	1
2013	1	0	1
2014	1	0	1
2015	0	1	1
2018	1	0	1
2019	1	0	1
2020	0	1	1
2021	0	3	3
2024	1	0	1
2025	0	1	1

Below are the most recent publications written about "RNA Stability" by people in Profiles.

Ibrahim F, Mourelatos Z. Defining the True Native Ends of RNAs at Single-Molecule Level with TERA-Seq. Methods Mol Biol. 2025; 2863:359-372.

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Vukovic I, Barnada SM, Ruffin JW, Karlin J, Lokareddy RK, Cingolani G, McMahon SB. Non-redundant roles for the human mRNA decapping cofactor paralogs DCP1a and DCP1b. Life Sci Alliance. 2024 Nov; 7(11).

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Li L, Sheng P, Li T, Fields CJ, Hiers NM, Wang Y, Li J, Guardia CM, Licht JD, Xie M. Widespread microRNA degradation elements in target mRNAs can assist the encoded proteins. Genes Dev. 2021 Dec 01; 35(23-24):1595-1609.

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George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P. RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site. Cell Rep. 2021 11 02; 37(5):109934.

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Ott IM, Strine MS, Watkins AE, Boot M, Kalinich CC, Harden CA, Vogels CBF, Casanovas-Massana A, Moore AJ, Muenker MC, Nakahata M, Tokuyama M, Nelson A, Fournier J, Bermejo S, Campbell M, Datta R, Dela Cruz CS, Farhadian SF, Ko AI, Iwasaki A, Grubaugh ND, Wilen CB, Wyllie AL. Stability of SARS-CoV-2 RNA in Nonsupplemented Saliva. Emerg Infect Dis. 2021 04; 27(4):1146-1150.

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Magee R, Rigoutsos I. On the expanding roles of tRNA fragments in modulating cell behavior. Nucleic Acids Res. 2020 09 25; 48(17):9433-9448.

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Nagarajan VK, Kukulich PM, von Hagel B, Green PJ. RNA degradomes reveal substrates and importance for dark and nitrogen stress responses of Arabidopsis XRN4. Nucleic Acids Res. 2019 09 26; 47(17):9216-9230.

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Ibrahim F, Maragkakis M, Alexiou P, Mourelatos Z. Ribothrypsis, a novel process of canonical mRNA decay, mediates ribosome-phased mRNA endonucleolysis. Nat Struct Mol Biol. 2018 04; 25(4):302-310.

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Kim HH, Lee SJ, Gardiner AS, Perrone-Bizzozero NI, Yoo S. Different motif requirements for the localization zipcode element of ?-actin mRNA binding by HuD and ZBP1. Nucleic Acids Res. 2015 Sep 03; 43(15):7432-46.

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Lee R, Xu B, Rame JE, Felkin LE, Barton P, Dries DL. Regulated inositol-requiring protein 1-dependent decay as a mechanism of corin RNA and protein deficiency in advanced human systolic heart failure. J Am Heart Assoc. 2014 Dec; 3(6):e001104.

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