Hepatocytes

"Hepatocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The main structural component of the LIVER. They are specialized EPITHELIAL CELLS that are organized into interconnected plates called lobules.

Descriptor ID	D022781
MeSH Number(s)	A11.436.348
Concept/Terms	Hepatocytes Hepatocytes Hepatocyte Hepatic Cells Cell, Hepatic Cells, Hepatic Hepatic Cell

Below are MeSH descriptors whose meaning is more general than "Hepatocytes".

Anatomy [A]
Cells [A11]
Epithelial Cells [A11.436]
Hepatocytes [A11.436.348]

Below are MeSH descriptors whose meaning is more specific than "Hepatocytes".

Hepatocytes
Hep G2 Cells

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hepatocytes" by people in this website by year, and whether "Hepatocytes" was a major or minor topic of these publications.

Bar chart showing 101 publications over 23 distinct years, with a maximum of 11 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2001	4	1	5
2002	0	1	1
2003	7	3	10
2004	3	0	3
2005	1	6	7
2006	1	4	5
2007	4	0	4
2008	3	1	4
2009	1	4	5
2010	3	1	4
2012	2	2	4
2013	3	3	6
2014	4	5	9
2015	5	2	7
2016	7	4	11
2017	4	2	6
2018	1	0	1
2020	1	2	3
2021	0	1	1
2022	1	0	1
2023	0	2	2
2025	1	0	1

Below are the most recent publications written about "Hepatocytes" by people in Profiles.

Ritzenthaler JD, Ekuban A, Horsman B, Roman J, Watson WH. Alcohol-induced liver injury is mediated via a4-containing nicotinic acetylcholine receptors expressed in hepatocytes. Alcohol Clin Exp Res (Hoboken). 2025 Mar; 49(3):515-525.

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Carlier J, Malaca S, Huestis MA, Tagliabracci A, Tini A, Busard? FP. Biomarkers of 4-hydroxy-N,N-methylpropyltryptamine (4-OH-MPT) intake identified from human hepatocyte incubations. Expert Opin Drug Metab Toxicol. 2022 Dec; 18(12):831-840.

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Parrow NL, Fleming RE. Transferrin receptor 1: keeper of HFE. Blood. 2023 Jan 26; 141(4):332-333.

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Hamidi A, Wolf A, Dueva R, Kaufmann M, G?pelt K, Iliakis G, Metzen E. Depletion of HIF-1a by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in Hypoxia. Cells. 2022 05 18; 11(10).

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Melo-Silva CR, Alves-Peixoto P, Heath N, Tang L, Montoya B, Knudson CJ, Stotesbury C, Ferez M, Wong E, Sigal LJ. Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells. PLoS Pathog. 2021 05; 17(5):e1009593.

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Carlier J, Diao X, Giorgetti R, Busard? FP, Huestis MA. Pyrrolidinyl Synthetic Cathinones a-PHP and 4F-a-PVP Metabolite Profiling Using Human Hepatocyte Incubations. Int J Mol Sci. 2020 Dec 28; 22(1).

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Chen J, Argemi J, Odena G, Xu MJ, Cai Y, Massey V, Parrish A, Vadigepalli R, Altamirano J, Cabezas J, Gines P, Caballeria J, Snider N, Sancho-Bru P, Akira S, Rusyn I, Gao B, Bataller R. Hepatic lipocalin 2 promotes liver fibrosis and portal hypertension. Sci Rep. 2020 09 23; 10(1):15558.

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Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller KD, Schug ZT, Snyder NW, Gade TP, Titchenell PM, Rabinowitz JD, Wellen KE. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 2020 03; 579(7800):586-591.

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Carlier J, Diao X, Huestis MA. Synthetic cannabinoid BB-22 (QUCHIC): Human hepatocytes metabolism with liquid chromatography-high resolution mass spectrometry detection. J Pharm Biomed Anal. 2018 Aug 05; 157:27-35.

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Niu C, Li L, Daffis S, Lucifora J, Bonnin M, Maadadi S, Salas E, Chu R, Ramos H, Livingston CM, Beran RK, Garg AV, Balsitis S, Durantel D, Zoulim F, Delaney WE, Fletcher SP. Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism. J Hepatol. 2018 05; 68(5):922-931.

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