Endpoint Determination

"Endpoint Determination" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Establishment of the level of a quantifiable effect indicative of a biologic process. The evaluation is frequently to detect the degree of toxic or therapeutic effect.

Descriptor ID	D023381
MeSH Number(s)	E05.315
Concept/Terms	Endpoint Determination Endpoint Determination Determination, Endpoint Determinations, Endpoint Endpoint Determinations End Point Determination Determinations, End Point End Point Determinations Point Determinations, End Endpoint Assay Endpoint Assay Assay, Endpoint Assays, Endpoint Endpoint Assays End Point Assay Assay, End Point Assays, End Point End Point Assays Point Assay, End Point Assays, End

Below are MeSH descriptors whose meaning is more general than "Endpoint Determination".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Endpoint Determination [E05.315]

Below are MeSH descriptors whose meaning is related to "Endpoint Determination".

Below are MeSH descriptors whose meaning is more specific than "Endpoint Determination".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Endpoint Determination" by people in this website by year, and whether "Endpoint Determination" was a major or minor topic of these publications.

Bar chart showing 35 publications over 17 distinct years, with a maximum of 6 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	1	1
2004	0	1	1
2005	1	1	2
2006	0	1	1
2007	0	1	1
2008	2	4	6
2009	0	4	4
2010	0	3	3
2011	0	2	2
2012	1	1	2
2013	0	1	1
2015	2	1	3
2016	0	1	1
2017	2	2	4
2018	0	1	1
2019	0	1	1
2020	0	1	1

Below are the most recent publications written about "Endpoint Determination" by people in Profiles.

Psotka MA, Abraham WT, Fiuzat M, Filippatos G, Lindenfeld J, Ahmad T, Bhatt AS, Carson PE, Cleland JGF, Felker GM, Januzzi JL, Kitzman DW, Leifer ES, Lewis EF, McMurray JJV, Mentz RJ, Solomon SD, Stockbridge N, Teerlink JR, Vaduganathan M, Vardeny O, Whellan DJ, Wittes J, Anker SD, O'Connor CM. Conduct of Clinical Trials in the Era of COVID-19: JACC Scientific Expert Panel. J Am Coll Cardiol. 2020 11 17; 76(20):2368-2378.

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Alak A, Hohnloser SH, Fr??dorf M, Reilly P, Ezekowitz M, Healey JS, Brueckmann M, Yusuf S, Connolly SJ. Reasons for hospitalization and risk of mortality in patients with atrial fibrillation treated with dabigatran or warfarin in the Randomized Evaluation of Long-term Anticoagulation Therapy (RE-LY) trial. Europace. 2019 Jul 01; 21(7):1023-1030.

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Ruiz CE, Hahn RT, Berrebi A, Borer JS, Cutlip DE, Fontana G, Gerosa G, Ibrahim R, Jelnin V, Jilaihawi H, Jolicoeur EM, Kliger C, Kronzon I, Leipsic J, Maisano F, Millan X, Nataf P, O'Gara PT, Pibarot P, Ramee SR, Rihal CS, Rodes-Cabau J, Sorajja P, Suri R, Swain JA, Turi ZG, Tuzcu EM, Weissman NJ, Zamorano JL, Serruys PW, Leon MB. Clinical Trial Principles and Endpoint Definitions for Paravalvular Leaks in Surgical Prosthesis. Eur Heart J. 2018 04 14; 39(15):1224-1245.

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Roviello G, Andre F, Venturini S, Pistilli B, Curigliano G, Cristofanilli M, Rosellini P, Generali D. Response rate as a potential surrogate for survival and efficacy in patients treated with novel immune checkpoint inhibitors: A meta-regression of randomised prospective studies. Eur J Cancer. 2017 11; 86:257-265.

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Nourzadeh H, Watkins WT, Ahmed M, Hui C, Schlesinger D, Siebers JV. Clinical adequacy assessment of autocontours for prostate IMRT with meaningful endpoints. Med Phys. 2017 Apr; 44(4):1525-1537.

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Gillam LD, Leipsic J, Weissman NJ. Use of Imaging Endpoints in Clinical Trials. JACC Cardiovasc Imaging. 2017 03; 10(3):296-303.

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Klinkhammer BM, Goldschmeding R, Floege J, Boor P. Treatment of Renal Fibrosis-Turning Challenges into Opportunities. Adv Chronic Kidney Dis. 2017 03; 24(2):117-129.

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Katz MG, Fargnoli AS, Kendle AP, Hajjar RJ, Bridges CR. Gene Therapy in Cardiac Surgery: Clinical Trials, Challenges, and Perspectives. Ann Thorac Surg. 2016 Jun; 101(6):2407-16.

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Sommer P, Kircher S, Rolf S, John S, Arya A, Dinov B, Richter S, Bollmann A, Hindricks G. Successful Repeat Catheter Ablation of Recurrent Longstanding Persistent Atrial Fibrillation With Rotor Elimination as the Procedural Endpoint: A Case Series. J Cardiovasc Electrophysiol. 2016 Mar; 27(3):274-80.

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Minion LE, Coleman RL, Alvarez RD, Herzog TJ. Endpoints in clinical trials: What do patients consider important? A survey of the Ovarian Cancer National Alliance. Gynecol Oncol. 2016 Feb; 140(2):193-8.

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