Heterogeneous-Nuclear Ribonucleoproteins
"Heterogeneous-Nuclear Ribonucleoproteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of ribonucleoproteins that were originally found as proteins bound to nascent RNA transcripts in the form of ribonucleoprotein particles. Although considered ribonucleoproteins they are primarily classified by their protein component. They are involved in a variety of processes such as packaging of RNA and RNA TRANSPORT within the nucleus. A subset of heterogeneous-nuclear ribonucleoproteins are involved in additional functions such as nucleocytoplasmic transport (ACTIVE TRANSPORT, CELL NUCLEUS) of RNA and mRNA stability in the CYTOPLASM.
| Descriptor ID |
D034441
|
| MeSH Number(s) |
D12.776.157.725.813.750 D12.776.664.962.813.750
|
| Concept/Terms |
Heterogeneous-Nuclear Ribonucleoproteins- Heterogeneous-Nuclear Ribonucleoproteins
- Heterogeneous Nuclear Ribonucleoproteins
- Ribonucleoproteins, Heterogeneous-Nuclear
- hnRNP
- Informofer
- Heterogeneous Nuclear Ribonucleoprotein
- Nuclear Ribonucleoprotein, Heterogeneous
- Ribonucleoprotein, Heterogeneous Nuclear
|
Below are MeSH descriptors whose meaning is more general than "Heterogeneous-Nuclear Ribonucleoproteins".
Below are MeSH descriptors whose meaning is more specific than "Heterogeneous-Nuclear Ribonucleoproteins".
This graph shows the total number of publications written about "Heterogeneous-Nuclear Ribonucleoproteins" by people in this website by year, and whether "Heterogeneous-Nuclear Ribonucleoproteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "Heterogeneous-Nuclear Ribonucleoproteins" by people in Profiles.
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Chang JS, Santhanam R, Trotta R, Neviani P, Eiring AM, Briercheck E, Ronchetti M, Roy DC, Calabretta B, Caligiuri MA, Perrotti D. High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiation. Blood. 2007 Aug 1; 110(3):994-1003.
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Perrotti D, Calabretta B. Translational regulation by the p210 BCR/ABL oncoprotein. Oncogene. 2004 Apr 19; 23(18):3222-9.
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Iervolino A, Santilli G, Trotta R, Guerzoni C, Cesi V, Bergamaschi A, Gambacorti-Passerini C, Calabretta B, Perrotti D. hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesis. Mol Cell Biol. 2002 Apr; 22(7):2255-66.
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Perrotti D, Cesi V, Trotta R, Guerzoni C, Santilli G, Campbell K, Iervolino A, Condorelli F, Gambacorti-Passerini C, Caligiuri MA, Calabretta B. BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2. Nat Genet. 2002 Jan; 30(1):48-58.
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Waterhouse N, Kumar S, Song Q, Strike P, Sparrow L, Dreyfuss G, Alnemri ES, Litwack G, Lavin M, Watters D. Heteronuclear ribonucleoproteins C1 and C2, components of the spliceosome, are specific targets of interleukin 1beta-converting enzyme-like proteases in apoptosis. J Biol Chem. 1996 Nov 15; 271(46):29335-41.