"Lamin Type A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of developmentally regulated lamins having a neutral isoelectric point. They are found to disassociate from nuclear membranes during mitosis.
| Descriptor ID |
D034904
|
| MeSH Number(s) |
D12.776.660.650.875.500
|
| Concept/Terms |
Lamin Type A- Lamin Type A
- Lamin A
- Type A Lamins
- Lamins, Type A
- Lamin A-C
- Lamin A C
|
Below are MeSH descriptors whose meaning is more general than "Lamin Type A".
Below are MeSH descriptors whose meaning is more specific than "Lamin Type A".
This graph shows the total number of publications written about "Lamin Type A" by people in this website by year, and whether "Lamin Type A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 5 | 0 | 5 |
| 2014 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lamin Type A" by people in Profiles.
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Sikder K, Phillips E, Zhong Z, Wang N, Saunders J, Mothy D, Kossenkov A, Schneider T, Nichtova Z, Csordas G, Margulies KB, Choi JC. Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy. Sci Adv. 2024 May 10; 10(19):eadh0798.
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Saunders J, Sikder K, Phillips E, Ishwar A, Mothy D, Margulies KB, Choi JC. Med25 Limits Master Regulators That Govern Adipogenesis. Int J Mol Sci. 2023 Mar 24; 24(7).
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Fu Y, Eisen HJ. Genetics of Dilated Cardiomyopathy. Curr Cardiol Rep. 2018 09 27; 20(11):121.
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Choi JC, Worman HJ. Nuclear envelope regulation of signaling cascades. Adv Exp Med Biol. 2014; 773:187-206.
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Choi JC, Wu W, Muchir A, Iwata S, Homma S, Worman HJ. Dual specificity phosphatase 4 mediates cardiomyopathy caused by lamin A/C (LMNA) gene mutation. J Biol Chem. 2012 Nov 23; 287(48):40513-24.
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Choi JC, Worman HJ. Reactivation of autophagy ameliorates LMNA cardiomyopathy. Autophagy. 2013 Jan; 9(1):110-1.
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Wang Y, Ostlund C, Choi JC, Swayne TC, Gundersen GG, Worman HJ. Blocking farnesylation of the prelamin A variant in Hutchinson-Gilford progeria syndrome alters the distribution of A-type lamins. Nucleus. 2012 Sep-Oct; 3(5):452-62.
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Choi JC, Muchir A, Wu W, Iwata S, Homma S, Morrow JP, Worman HJ. Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation. Sci Transl Med. 2012 Jul 25; 4(144):144ra102.
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Muchir A, Wu W, Choi JC, Iwata S, Morrow J, Homma S, Worman HJ. Abnormal p38a mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation. Hum Mol Genet. 2012 Oct 01; 21(19):4325-33.
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Ostlund C, Folker ES, Choi JC, Gomes ER, Gundersen GG, Worman HJ. Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins. J Cell Sci. 2009 Nov 15; 122(Pt 22):4099-108.