Cardiomyopathy, Dilated

"Cardiomyopathy, Dilated" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.

Descriptor ID	D002311
MeSH Number(s)	C14.280.195.160 C14.280.238.070
Concept/Terms	Cardiomyopathy, Dilated Cardiomyopathy, Dilated Cardiomyopathies, Dilated Dilated Cardiomyopathies Dilated Cardiomyopathy Cardiomyopathy, Familial Idiopathic Cardiomyopathy, Familial Idiopathic Cardiomyopathies, Familial Idiopathic Familial Idiopathic Cardiomyopathies Familial Idiopathic Cardiomyopathy Idiopathic Cardiomyopathies, Familial Idiopathic Cardiomyopathy, Familial Cardiomyopathy, Congestive Cardiomyopathies, Congestive Congestive Cardiomyopathies Cardiomyopathy, Dilated, with Conduction Deffect1 Cardiomyopathy, Dilated, CMD1A Dilated cardiomyopathy 1A 1As, Dilated cardiomyopathy Dilated cardiomyopathy 1As cardiomyopathy 1A, Dilated cardiomyopathy 1As, Dilated Cardiomyopathy, Dilated, Autosomal Recessive Cardiomyopathy, Dilated, 1a Cardiomyopathy, Dilated, With Conduction Defect 1 Cardiomyopathy, Idiopathic Dilated Cardiomyopathies, Idiopathic Dilated Dilated Cardiomyopathies, Idiopathic Dilated Cardiomyopathy, Idiopathic Idiopathic Dilated Cardiomyopathies Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Cardiomyopathy, Dilated, LMNA

Below are MeSH descriptors whose meaning is more general than "Cardiomyopathy, Dilated".

Diseases [C]
Cardiovascular Diseases [C14]
Heart Diseases [C14.280]
Cardiomegaly [C14.280.195]
Cardiomyopathy, Dilated [C14.280.195.160]
Cardiomyopathies [C14.280.238]
Cardiomyopathy, Dilated [C14.280.238.070]

Below are MeSH descriptors whose meaning is related to "Cardiomyopathy, Dilated".

Below are MeSH descriptors whose meaning is more specific than "Cardiomyopathy, Dilated".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cardiomyopathy, Dilated" by people in this website by year, and whether "Cardiomyopathy, Dilated" was a major or minor topic of these publications.

Bar chart showing 76 publications over 25 distinct years, with a maximum of 9 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	2	1	3
1998	2	1	3
1999	1	1	2
2000	1	1	2
2001	1	0	1
2002	1	0	1
2003	1	1	2
2005	0	1	1
2006	1	0	1
2007	4	2	6
2008	3	0	3
2009	1	2	3
2010	0	1	1
2011	4	0	4
2012	4	0	4
2013	4	0	4
2014	5	2	7
2015	8	1	9
2017	1	0	1
2018	2	0	2
2019	4	0	4
2020	3	0	3
2021	2	1	3
2023	2	0	2
2024	4	0	4

Below are the most recent publications written about "Cardiomyopathy, Dilated" by people in Profiles.

Garg A, Jansen S, Greenberg L, Zhang R, Lavine KJ, Greenberg MJ. Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility. Proc Natl Acad Sci U S A. 2024 11 12; 121(46):e2405020121.

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Mazur M, Bhat G, Popjes E, Dowling R, Eisen HJ. Long-term post-transplantation outcomes in patients with hypertrophic cardiomyopathy: Single-center 35-year experience. Clin Transplant. 2024 02; 38(2):e15265.

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Nigam P, Fitzgerald KK, Scavina M, Tsuda T. Diverse Cardiac Phenotype of Becker Muscular Dystrophy: Under-Recognized Subclinical Cardiomyopathy Due to Partial Dystrophin Deficiency in a Contemporary Era. Pediatr Cardiol. 2025 Feb; 46(2):267-278.

View in: PubMed
Ghahremani S, Kanwal A, Pettinato A, Ladha F, Legere N, Thakar K, Zhu Y, Tjong H, Wilderman A, Stump WT, Greenberg L, Greenberg MJ, Cotney J, Wei CL, Hinson JT. CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by TTN Truncation Variants. Circulation. 2024 Apr 16; 149(16):1285-1297.

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Scott B, Greenberg MJ. Multiscale biophysical models of cardiomyopathies reveal complexities challenging existing dogmas. Biophys J. 2023 12 19; 122(24):4632-4634.

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Barrick SK, Garg A, Greenberg L, Zhang S, Lin CY, Stitziel NO, Greenberg MJ. Functional assays reveal the pathogenic mechanism of a de novo tropomyosin variant identified in patient with dilated cardiomyopathy. J Mol Cell Cardiol. 2023 03; 176:58-67.

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Wong NR, Mohan J, Kopecky BJ, Guo S, Du L, Leid J, Feng G, Lokshina I, Dmytrenko O, Luehmann H, Bajpai G, Ewald L, Bell L, Patel N, Bredemeyer A, Weinheimer CJ, Nigro JM, Kovacs A, Morimoto S, Bayguinov PO, Fisher MR, Stump WT, Greenberg M, Fitzpatrick JAJ, Epelman S, Kreisel D, Sah R, Liu Y, Hu H, Lavine KJ. Resident cardiac macrophages mediate adaptive myocardial remodeling. Immunity. 2021 09 14; 54(9):2072-2088.e7.

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Barrick SK, Greenberg L, Greenberg MJ. A troponin T variant linked with pediatric dilated cardiomyopathy reduces the coupling of thin filament activation to myosin and calcium binding. Mol Biol Cell. 2021 08 19; 32(18):1677-1689.

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Alloah Q, Pelletier G, Prada-Ruiz AC, Tsuda T. Rapid Growth of Left Atrial Thrombus in a Pediatric Heart Transplant Recipient. Ann Thorac Surg. 2022 02; 113(2):e133-e135.

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Cully M, Attia MW. Young Child With Dyspnea and Vomiting. Ann Emerg Med. 2020 11; 76(5):680-694.

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