"Ephrin-B2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane domain containing ephrin that binds with high affinity to EPHB1 RECEPTOR; EPHB3 RECEPTOR; and EPHB4 RECEPTOR. Expression of ephrin-B2 occurs in a variety of adult tissues. During embryogenesis, high levels of ephrin-B2 is seen in the PROSENCEPHALON; RHOMBENCEPHALON; developing SOMITES; LIMB BUD; and bronchial arches.
| Descriptor ID |
D036388
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| MeSH Number(s) |
D12.644.276.500.700 D12.776.467.500.700 D12.776.543.287.700 D23.529.500.700
|
| Concept/Terms |
Ephrin-B2- Ephrin-B2
- Ephrin B2
- LERK-5 Gene Product
- LERK 5 Gene Product
- Efbn2 Gene Product
- Eplg5 Gene Product
- LERK-5 Protein
- LERK 5 Protein
- Eplg5 Protein
Eph Ligand Family 2 Protein, Mammalian- Eph Ligand Family 2 Protein, Mammalian
- Htk Ligand
- Ligand, Htk
- Mammalian ELF-2
- ELF-2, Mammalian
- Mammalian ELF 2
- HTKL Protein
- ELF-2 Protein, Mammalian
- ELF 2 Protein, Mammalian
- Mammalian ELF-2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Ephrin-B2".
Below are MeSH descriptors whose meaning is more specific than "Ephrin-B2".
This graph shows the total number of publications written about "Ephrin-B2" by people in this website by year, and whether "Ephrin-B2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Ephrin-B2" by people in Profiles.
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Lennon S, Oweida A, Milner D, Phan AV, Bhatia S, Van Court B, Darragh L, Mueller AC, Raben D, Martínez-Torrecuadrada JL, Pitts TM, Somerset H, Jordan KR, Hansen KC, Williams J, Messersmith WA, Schulick RD, Owens P, Goodman KA, Karam SD. Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination. Clin Cancer Res. 2019 06 01; 25(11):3352-3365.
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Bhatia S, Oweida A, Lennon S, Darragh LB, Milner D, Phan AV, Mueller AC, Van Court B, Raben D, Serkova NJ, Wang XJ, Jimeno A, Clambey ET, Pasquale EB, Karam SD. Inhibition of EphB4-Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers. Cancer Res. 2019 05 15; 79(10):2722-2735.
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Meijome TE, Ekwealor JTB, Hooker RA, Cheng YH, Ciovacco WA, Balamohan SM, Srinivasan TL, Chitteti BR, Eleniste PP, Horowitz MC, Srour EF, Bruzzaniti A, Fuchs RK, Kacena MA. C-Mpl Is Expressed on Osteoblasts and Osteoclasts and Is Important in Regulating Skeletal Homeostasis. J Cell Biochem. 2016 04; 117(4):959-69.
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McClelland AC, Hruska M, Coenen AJ, Henkemeyer M, Dalva MB. Trans-synaptic EphB2-ephrin-B3 interaction regulates excitatory synapse density by inhibition of postsynaptic MAPK signaling. Proc Natl Acad Sci U S A. 2010 May 11; 107(19):8830-5.
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McClelland AC, Sheffler-Collins SI, Kayser MS, Dalva MB. Ephrin-B1 and ephrin-B2 mediate EphB-dependent presynaptic development via syntenin-1. Proc Natl Acad Sci U S A. 2009 Dec 1; 106(48):20487-92.
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Takasu MA, Dalva MB, Zigmond RE, Greenberg ME. Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors. Science. 2002 Jan 18; 295(5554):491-5.