"ADP-ribosyl Cyclase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane-bound or cytosolic enzyme that catalyzes the synthesis of CYCLIC ADP-RIBOSE (cADPR) from nicotinamide adenine dinucleotide (NAD). This enzyme generally catalyzes the hydrolysis of cADPR to ADP-RIBOSE, as well, and sometimes the synthesis of cyclic ADP-ribose 2' phosphate (2'-P-cADPR) from NADP.
| Descriptor ID |
D036541
|
| MeSH Number(s) |
D08.811.277.450.430.400.060 D08.811.913.400.725.115.660.060
|
| Concept/Terms |
ADP-ribosyl Cyclase- ADP-ribosyl Cyclase
- ADP ribosyl Cyclase
- Cyclase, ADP-ribosyl
- ADPR Cyclase
- Cyclase, ADPR
- Adenosine Diphosphate Ribose Cyclase
- ADP Ribose Cyclase
- Cyclase, ADP Ribose
- Ribose Cyclase, ADP
Cyclic ADP-ribose Hydrolase- Cyclic ADP-ribose Hydrolase
- ADP-ribose Hydrolase, Cyclic
- Cyclic ADP ribose Hydrolase
- Hydrolase, Cyclic ADP-ribose
- cADPR Hydrolase
- Hydrolase, cADPR
2'-P-ADPR Cyclase- 2'-P-ADPR Cyclase
- 2' P ADPR Cyclase
- Cyclase, 2'-P-ADPR
- 2'-Phospho-adenosine Diphosphate Ribose Cyclase
- 2' Phospho adenosine Diphosphate Ribose Cyclase
|
Below are MeSH descriptors whose meaning is more general than "ADP-ribosyl Cyclase".
Below are MeSH descriptors whose meaning is more specific than "ADP-ribosyl Cyclase".
This graph shows the total number of publications written about "ADP-ribosyl Cyclase" by people in this website by year, and whether "ADP-ribosyl Cyclase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 4 | 1 | 5 |
| 2005 | 1 | 1 | 2 |
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click here.
Below are the most recent publications written about "ADP-ribosyl Cyclase" by people in Profiles.
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Kang BN, Deshpande DA, Tirumurugaan KG, Panettieri RA, Walseth TF, Kannan MS. Adenoviral mediated anti-sense CD38 attenuates TNF-alpha-induced changes in calcium homeostasis of human airway smooth muscle cells. Can J Physiol Pharmacol. 2005 Aug-Sep; 83(8-9):799-804.
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Deshpande DA, White TA, Dogan S, Walseth TF, Panettieri RA, Kannan MS. CD38/cyclic ADP-ribose signaling: role in the regulation of calcium homeostasis in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2005 May; 288(5):L773-88.
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Deshpande DA, White TA, Guedes AG, Milla C, Walseth TF, Lund FE, Kannan MS. Altered airway responsiveness in CD38-deficient mice. Am J Respir Cell Mol Biol. 2005 Feb; 32(2):149-56.
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Kotlikoff MI, Kannan MS, Solway J, Deng KY, Deshpande DA, Dowell M, Feldman M, Green KS, Ji G, Johnston R, Lakser O, Lee J, Lund FE, Milla C, Mitchell RW, Nakai J, Rishniw M, Walseth TF, White TA, Wilson J, Xin HB, Woodruff PG. Methodologic advancements in the study of airway smooth muscle. J Allergy Clin Immunol. 2004 Aug; 114(2 Suppl):S18-31.
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Tliba O, Panettieri RA, Tliba S, Walseth TF, Amrani Y. Tumor necrosis factor-alpha differentially regulates the expression of proinflammatory genes in human airway smooth muscle cells by activation of interferon-beta-dependent CD38 pathway. Mol Pharmacol. 2004 Aug; 66(2):322-9.
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Dogan S, Deshpande DA, Kannan MS, Walseth TF. Changes in CD38 expression and ADP-ribosyl cyclase activity in rat myometrium during pregnancy: influence of sex steroid hormones. Biol Reprod. 2004 Jul; 71(1):97-103.
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Deshpande DA, Dogan S, Walseth TF, Miller SM, Amrani Y, Panettieri RA, Kannan MS. Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of CD38/cyclic adenosine diphosphate ribose pathway. Am J Respir Cell Mol Biol. 2004 Jul; 31(1):36-42.
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Deshpande DA, Walseth TF, Panettieri RA, Kannan MS. CD38/cyclic ADP-ribose-mediated Ca2+ signaling contributes to airway smooth muscle hyper-responsiveness. FASEB J. 2003 Mar; 17(3):452-4.
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Dogan S, White TA, Deshpande DA, Murtaugh MP, Walseth TF, Kannan MS. Estrogen increases CD38 gene expression and leads to differential regulation of adenosine diphosphate (ADP)-ribosyl cyclase and cyclic ADP-ribose hydrolase activities in rat myometrium. Biol Reprod. 2002 Mar; 66(3):596-602.