"Photobleaching" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Light-induced change in a chromophore, resulting in the loss of its absorption of light of a particular wave length. The photon energy causes a conformational change in the photoreceptor proteins affecting PHOTOTRANSDUCTION. This occurs naturally in the retina (ADAPTATION, OCULAR) on long exposure to bright light. Photobleaching presents problems when occurring in PHOTODYNAMIC THERAPY, and in FLUORESCENCE MICROSCOPY. On the other hand, this phenomenon is exploited in the technique, FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING, allowing measurement of the movements of proteins and LIPIDS in the CELL MEMBRANE.
| Descriptor ID |
D038761
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| MeSH Number(s) |
G02.740.680
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Photobleaching".
Below are MeSH descriptors whose meaning is more specific than "Photobleaching".
This graph shows the total number of publications written about "Photobleaching" by people in this website by year, and whether "Photobleaching" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Photobleaching" by people in Profiles.
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Merianda TT, Coleman J, Kim HH, Kumar Sahoo P, Gomes C, Brito-Vargas P, Rauvala H, Blesch A, Yoo S, Twiss JL. Axonal amphoterin mRNA is regulated by translational control and enhances axon outgrowth. J Neurosci. 2015 Apr 08; 35(14):5693-706.
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Merianda TT, Gomes C, Yoo S, Vuppalanchi D, Twiss JL. Axonal localization of neuritin/CPG15 mRNA in neuronal populations through distinct 5' and 3' UTR elements. J Neurosci. 2013 Aug 21; 33(34):13735-42.
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Jensen DA, Steplewski A, Gawron K, Fertala A. Persistence of intracellular and extracellular changes after incompletely suppressing expression of the R789C (p.R989C) and R992C (p.R1192C) collagen II mutants. Hum Mutat. 2011 Jul; 32(7):794-805.
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Buch C, Hunt MC, Alexson SE, Hallberg E. Localization of peroxisomal matrix proteins by photobleaching. Biochem Biophys Res Commun. 2009 Oct 16; 388(2):355-9.