Methylenetetrahydrofolate Reductase (NADPH2)
"Methylenetetrahydrofolate Reductase (NADPH2)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein amine oxidoreductase that catalyzes the reversible conversion of 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. This enzyme was formerly classified as EC 1.1.1.171.
Descriptor ID |
D042965
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MeSH Number(s) |
D08.811.682.662.290 D12.776.331.775
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Concept/Terms |
Methylenetetrahydrofolate Reductase (NADPH2)- Methylenetetrahydrofolate Reductase (NADPH2)
- Methylenetetrahydrofolate Reductase (NADPH)
- Methylene-THF Reductase (NADPH)
- Methylenetetrahydrofolate Reductase
- 5,10-Methylenetetrahydrofolate Reductase (NADPH)
- Methylene Tetrahydrofolate Reductase
- Tetrahydrofolate Reductase, Methylene
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Below are MeSH descriptors whose meaning is more general than "Methylenetetrahydrofolate Reductase (NADPH2)".
Below are MeSH descriptors whose meaning is more specific than "Methylenetetrahydrofolate Reductase (NADPH2)".
This graph shows the total number of publications written about "Methylenetetrahydrofolate Reductase (NADPH2)" by people in this website by year, and whether "Methylenetetrahydrofolate Reductase (NADPH2)" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 2 | 0 | 2 |
2007 | 0 | 1 | 1 |
2009 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methylenetetrahydrofolate Reductase (NADPH2)" by people in Profiles.
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Argiris A, Karamouzis MV, Gooding WE, Branstetter BF, Zhong S, Raez LE, Savvides P, Romkes M. Phase II trial of pemetrexed and bevacizumab in patients with recurrent or metastatic head and neck cancer. J Clin Oncol. 2011 Mar 20; 29(9):1140-5.
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Tietjen GE, Herial NA, Utley C, White L, Yerga-Woolwine S, Joe B. Association of von Willebrand factor activity with ACE I/D and MTHFR C677T polymorphisms in migraine. Cephalalgia. 2009 Sep; 29(9):960-8.
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Mavragani CP, Patronas N, Dalakas M, Moutsopoulos HM. Ill-defined neurological syndromes with autoimmune background: a diagnostic challenge. J Rheumatol. 2007 Feb; 34(2):341-5.
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Matsubayashi H, Skinner HG, Iacobuzio-Donahue C, Abe T, Sato N, Riall TS, Yeo CJ, Kern SE, Goggins M. Pancreaticobiliary cancers with deficient methylenetetrahydrofolate reductase genotypes. Clin Gastroenterol Hepatol. 2005 Aug; 3(8):752-60.
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Jünemann AG, von Ahsen N, Reulbach U, Roedl J, Bönsch D, Kornhuber J, Kruse FE, Bleich S. C677T variant in the methylentetrahydrofolate reductase gene is a genetic risk factor for primary open-angle glaucoma. Am J Ophthalmol. 2005 Apr; 139(4):721-3.