"PPAR gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR ALPHA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES. It is a target of THIAZOLIDINEDIONES for control of DIABETES MELLITUS.
Descriptor ID |
D047495
|
MeSH Number(s) |
D12.776.826.239.588
|
Concept/Terms |
PPAR gamma- PPAR gamma
- PPARgamma
- Thiazolidinedione Receptor
- Receptor, Thiazolidinedione
- Peroxisome Proliferator-Activated Receptor gamma
- Peroxisome Proliferator Activated Receptor gamma
|
Below are MeSH descriptors whose meaning is more general than "PPAR gamma".
Below are MeSH descriptors whose meaning is more specific than "PPAR gamma".
This graph shows the total number of publications written about "PPAR gamma" by people in this website by year, and whether "PPAR gamma" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2005 | 6 | 5 | 11 |
2006 | 3 | 3 | 6 |
2007 | 4 | 3 | 7 |
2008 | 5 | 2 | 7 |
2009 | 6 | 1 | 7 |
2010 | 4 | 1 | 5 |
2011 | 2 | 1 | 3 |
2012 | 0 | 1 | 1 |
2013 | 1 | 0 | 1 |
2015 | 1 | 2 | 3 |
2016 | 1 | 1 | 2 |
2017 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "PPAR gamma" by people in Profiles.
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Saunders J, Sikder K, Phillips E, Ishwar A, Mothy D, Margulies KB, Choi JC. Med25 Limits Master Regulators That Govern Adipogenesis. Int J Mol Sci. 2023 Mar 24; 24(7).
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Zou Y, Watters A, Cheng N, Perry CE, Xu K, Alicea GM, Parris JLD, Baraban E, Ray P, Nayak A, Xu X, Herlyn M, Murphy ME, Weeraratna AT, Schug ZT, Chen Q. Polyunsaturated Fatty Acids from Astrocytes Activate PPAR? Signaling in Cancer Cells to Promote Brain Metastasis. Cancer Discov. 2019 12; 9(12):1720-1735.
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Sikder K, Shukla SK, Patel N, Singh H, Rafiq K. High Fat Diet Upregulates Fatty Acid Oxidation and Ketogenesis via Intervention of PPAR-?. Cell Physiol Biochem. 2018; 48(3):1317-1331.
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Singh SP, Chand HS, Langley RJ, Mishra N, Barrett T, Rudolph K, Tellez C, Filipczak PT, Belinsky S, Saeed AI, Sheybani A, Exil V, Agarwal H, Sidhaye VK, Sussan T, Biswal S, Sopori M. Gestational Exposure to Sidestream (Secondhand) Cigarette Smoke Promotes Transgenerational Epigenetic Transmission of Exacerbated Allergic Asthma and Bronchopulmonary Dysplasia. J Immunol. 2017 05 15; 198(10):3815-3822.
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Witt RL. Targeted Next Generation Sequencing with ThyroSeq v2.1 for Indeterminate Thyroid Nodules in Clinical Practice. Del Med J. 2016 Dec; 88(12):366-372.
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Handley N, Eide J, Taylor R, Wuertz B, Gaffney P, Ondrey F. PPAR? targeted oral cancer treatment and additional utility of genomics analytic techniques. Laryngoscope. 2017 04; 127(4):E124-E131.
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Roberts J, Bain PA, Kumar A, Hepplewhite C, Ellis DJ, Christy AG, Beavis SG. Tracking multiple modes of endocrine activity in Australia's largest inland sewage treatment plant and effluent- receiving environment using a panel of in vitro bioassays. Environ Toxicol Chem. 2015 Oct; 34(10):2271-81.
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Karahanian E, Rivera-Meza M, Quintanilla ME, Mu?oz D, Fern?ndez K, Israel Y. PPARa Agonists Reduce Alcohol Drinking: Do They Act in the Brain or in the Liver? Alcohol Alcohol. 2015 Nov; 50(6):717-8.
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Lakkaraju SK, Yu W, Raman EP, Hershfeld AV, Fang L, Deshpande DA, MacKerell AD. Mapping functional group free energy patterns at protein occluded sites: nuclear receptors and G-protein coupled receptors. J Chem Inf Model. 2015 Mar 23; 55(3):700-8.
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Biscetti F, Pecorini G, Arena V, Stigliano E, Angelini F, Ghirlanda G, Ferraccioli G, Flex A. Cilostazol improves the response to ischemia in diabetic mice by a mechanism dependent on PPAR?. Mol Cell Endocrinol. 2013 Dec 05; 381(1-2):80-7.