Receptors, Cytoplasmic and Nuclear

"Receptors, Cytoplasmic and Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.

Descriptor ID	D018160
MeSH Number(s)	D12.776.826
Concept/Terms	Receptors, Cytoplasmic and Nuclear Receptors, Cytoplasmic and Nuclear Receptors, Cytosol and Nuclear Cytosolic and Nuclear Receptors Receptors, Nuclear and Cytoplasmic Cytoplasmic and Nuclear Receptors Cytosol and Nuclear Receptors Nuclear and Cytoplasmic Receptors Receptors, Cytosolic and Nuclear Receptors, Nuclear Receptors, Nuclear Nuclear Receptors Receptors, Cytoplasmic Receptors, Cytoplasmic Cytoplasmic Receptors Receptors, Intracellular Membrane Receptors, Intracellular Membrane Membrane Receptors, Intracellular Intracellular Membrane Receptors Hormone Receptors, Cytoplasmic Hormone Receptors, Cytoplasmic Receptors, Cytoplasmic Hormone Cytoplasmic Hormone Receptors Hormone Receptors, Nuclear Hormone Receptors, Nuclear Receptors, Nuclear Hormone Nuclear Hormone Receptors

Below are MeSH descriptors whose meaning is more general than "Receptors, Cytoplasmic and Nuclear".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Receptors, Cytoplasmic and Nuclear [D12.776.826]

Below are MeSH descriptors whose meaning is related to "Receptors, Cytoplasmic and Nuclear".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Cytoplasmic and Nuclear".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Cytoplasmic and Nuclear" by people in this website by year, and whether "Receptors, Cytoplasmic and Nuclear" was a major or minor topic of these publications.

Bar chart showing 90 publications over 23 distinct years, with a maximum of 15 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	2	3
1997	4	3	7
1998	1	1	2
1999	3	0	3
2000	5	0	5
2001	2	1	3
2002	3	0	3
2003	9	1	10
2004	9	6	15
2005	4	0	4
2006	2	3	5
2007	3	1	4
2008	2	0	2
2009	1	1	2
2010	3	2	5
2011	1	3	4
2012	1	0	1
2013	2	0	2
2015	2	1	3
2021	0	1	1
2022	1	0	1
2023	0	2	2
2024	1	2	3

Below are the most recent publications written about "Receptors, Cytoplasmic and Nuclear" by people in Profiles.

Nie DY, Tabor JR, Li J, Kutera M, St-Germain J, Hanley RP, Wolf E, Paulakonis E, Kenney TMG, Duan S, Shrestha S, Owens DDG, Maitland MER, Pon A, Szewczyk M, Lamberto AJ, Menes M, Li F, Penn LZ, Barsyte-Lovejoy D, Brown NG, Barsotti AM, Stamford AW, Collins JL, Wilson DJ, Raught B, Licht JD, James LI, Arrowsmith CH. Recruitment of FBXO22 for targeted degradation of NSD2. Nat Chem Biol. 2024 Dec; 20(12):1597-1607.

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Chakravarti N, Boles A, Burzinski R, Sindaco P, Isabelle C, McConnell K, Mishra A, Porcu P. XPO1 blockade with KPT-330 promotes apoptosis in cutaneous T-cell lymphoma by activating the p53-p21 and p27 pathways. Sci Rep. 2024 04 23; 14(1):9305.

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Cicardi ME, Kankate V, Sriramoji S, Krishnamurthy K, Markandaiah SS, Verdone BM, Girdhar A, Nelson A, Rivas LB, Boehringer A, Haeusler AR, Pasinelli P, Guo L, Trotti D. The nuclear import receptor Kap?2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD. Commun Biol. 2024 03 28; 7(1):376.

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Morozov VM, Riva A, Sarwar S, Kim WJ, Li J, Zhou L, Licht JD, Daaka Y, Ishov AM. HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers. Nucleic Acids Res. 2023 10 27; 51(19):10194-10217.

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Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Beuve A, Brouckaert P, Bryant C, Burnett JC, Farndale RW, Friebe A, Garthwaite J, Hobbs AJ, Jarvis GE, Koesling D, Kuhn M, MacEwan D, Monie TP, Potter LR, Russwurm M, Schmidt HHHW, Stasch JP, Waldman SA. The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors. Br J Pharmacol. 2023 10; 180 Suppl 2:S241-S288.

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Ashton AW, Dhanjal HK, Rossner B, Mahmood H, Patel VI, Nadim M, Lota M, Shahid F, Li Z, Joyce D, Pajkos M, Doszt?nyi Z, Jiao X, Pestell RG. Acetylation of nuclear receptors in health and disease: an update. FEBS J. 2024 01; 291(2):217-236.

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Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Beuve A, Brouckaert P, Bryant C, Burnett JC, Farndale RW, Friebe A, Garthwaite J, Hobbs AJ, Jarvis GE, Kuhn M, MacEwan D, Monie TP, Papapetropoulos A, Potter LR, Schmidt HHHW, Szabo C, Waldman SA. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors. Br J Pharmacol. 2021 Oct; 178 Suppl 1:S264-S312.

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Duker AL, Eldridge G, Braverman NE, Bober MB. Congenital heart defects common in rhizomelic chondrodysplasia punctata. Am J Med Genet A. 2016 Jan; 170A(1):270-2.

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Attiyeh EF, Maris JM, Lock R, Reynolds CP, Kang MH, Carol H, Gorlick R, Kolb EA, Keir ST, Wu J, Landesman Y, Shacham S, Lyalin D, Kurmasheva RT, Houghton PJ, Smith MA. Pharmacodynamic and genomic markers associated with response to the XPO1/CRM1 inhibitor selinexor (KPT-330): A report from the pediatric preclinical testing program. Pediatr Blood Cancer. 2016 Feb; 63(2):276-86.

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Yao PL, Chen L, Hess RA, M?ller R, Gonzalez FJ, Peters JM. Peroxisome Proliferator-activated Receptor-D (PPARD) Coordinates Mouse Spermatogenesis by Modulating Extracellular Signal-regulated Kinase (ERK)-dependent Signaling. J Biol Chem. 2015 Sep 18; 290(38):23416-31.

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