"TRPC Cation Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of TRP cation channels that contain 3-4 ANKYRIN REPEAT DOMAINS and a conserved C-terminal domain. Members are highly expressed in the CENTRAL NERVOUS SYSTEM. Selectivity for calcium over sodium ranges from 0.5 to 10.
| Descriptor ID |
D050052
|
| MeSH Number(s) |
D12.776.157.530.400.901.500 D12.776.543.585.400.901.500
|
| Concept/Terms |
TRPC Cation Channels- TRPC Cation Channels
- Cation Channels, TRPC
- Channels, TRPC Cation
- Transient Receptor Potential Channels, Type C
- Transient Receptor Potential Cation Channel Subfamily C
|
Below are MeSH descriptors whose meaning is more general than "TRPC Cation Channels".
Below are MeSH descriptors whose meaning is more specific than "TRPC Cation Channels".
This graph shows the total number of publications written about "TRPC Cation Channels" by people in this website by year, and whether "TRPC Cation Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "TRPC Cation Channels" by people in Profiles.
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Brailoiu GC, Brailoiu E. Modulation of Calcium Entry by the Endo-lysosomal System. Adv Exp Med Biol. 2016; 898:423-47.
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Barr JL, Deliu E, Brailoiu GC, Zhao P, Yan G, Abood ME, Unterwald EM, Brailoiu E. Mechanisms of activation of nucleus accumbens neurons by cocaine via sigma-1 receptor-inositol 1,4,5-trisphosphate-transient receptor potential canonical channel pathways. Cell Calcium. 2015 Aug; 58(2):196-207.
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Edelmayer RM, Le LN, Yan J, Wei X, Nassini R, Materazzi S, Preti D, Appendino G, Geppetti P, Dodick DW, Vanderah TW, Porreca F, Dussor G. Activation of TRPA1 on dural afferents: a potential mechanism of headache pain. Pain. 2012 Sep; 153(9):1949-1958.
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Ahmmed GU, Mehta D, Vogel S, Holinstat M, Paria BC, Tiruppathi C, Malik AB. Protein kinase Calpha phosphorylates the TRPC1 channel and regulates store-operated Ca2+ entry in endothelial cells. J Biol Chem. 2004 May 14; 279(20):20941-9.
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Mehta D, Ahmmed GU, Paria BC, Holinstat M, Voyno-Yasenetskaya T, Tiruppathi C, Minshall RD, Malik AB. RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability. J Biol Chem. 2003 Aug 29; 278(35):33492-500.