Complement C1 Inhibitor Protein

"Complement C1 Inhibitor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.

Descriptor ID	D050718
MeSH Number(s)	D12.644.861.140.500 D12.776.124.486.274.920.250.500 D12.776.395.320 D12.776.872.140.500
Concept/Terms	Complement C1 Inhibitor Protein Complement C1 Inhibitor Protein Serpin Family G Member 1 C1 Esterase Inhibitor Esterase Inhibitor, C1 C1-Inhibitor Protein C1 Inhibitor Protein Serpin G1 G1, Serpin Plasma Protease C1 Inhibitor Complement C1-Inhibitor Protein SERPING1 C1-INH Protein C1 INH Protein

Below are MeSH descriptors whose meaning is more general than "Complement C1 Inhibitor Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Serpins [D12.644.861]
Complement C1 Inactivator Proteins [D12.644.861.140]
Complement C1 Inhibitor Protein [D12.644.861.140.500]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Immunoproteins [D12.776.124.486]
Complement System Proteins [D12.776.124.486.274]
Complement Inactivator Proteins [D12.776.124.486.274.920]
Complement C1 Inactivator Proteins [D12.776.124.486.274.920.250]
Complement C1 Inhibitor Protein [D12.776.124.486.274.920.250.500]
Glycoproteins [D12.776.395]
Complement C1 Inhibitor Protein [D12.776.395.320]
Serpins [D12.776.872]
Complement C1 Inactivator Proteins [D12.776.872.140]
Complement C1 Inhibitor Protein [D12.776.872.140.500]

Below are MeSH descriptors whose meaning is more specific than "Complement C1 Inhibitor Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Complement C1 Inhibitor Protein" by people in this website by year, and whether "Complement C1 Inhibitor Protein" was a major or minor topic of these publications.

Bar chart showing 9 publications over 6 distinct years, with a maximum of 3 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2010	1	2	3
2011	1	0	1
2012	1	0	1
2017	2	0	2
2019	1	0	1
2020	0	1	1

Below are the most recent publications written about "Complement C1 Inhibitor Protein" by people in Profiles.

Tanaka KA, Mondal S, Morita Y, Williams B, Strauss ER, Cicardi M. Perioperative Management of Patients With Hereditary Angioedema With Special Considerations for Cardiopulmonary Bypass. Anesth Analg. 2020 07; 131(1):155-169.

View in: PubMed
Perza M, Koczirka S, Nomura JT. C1 Esterase Inhibitor for Ace-Inhibitor Angioedema: A Case Series and Literature Review. J Emerg Med. 2020 Mar; 58(3):e121-e127.

View in: PubMed
Sanfilippo C, Cambria D, Longo A, Palumbo M, Avola R, Pinzone M, Nunnari G, Condorelli F, Musumeci G, Imbesi R, Castogiovanni P, Malaguarnera L, Di Rosa M. SERPING1 mRNA overexpression in monocytes from HIV+ patients. Inflamm Res. 2017 Dec; 66(12):1107-1116.

View in: PubMed
Wygrecka M, Kosanovic D, Wujak L, Reppe K, Henneke I, Frey H, Didiasova M, Kwapiszewska G, Marsh LM, Baal N, Hackstein H, Zakrzewicz D, M?ller-Redetzky HC, de Maat S, Maas C, Nolte MW, Panousis C, Schermuly RT, Seeger W, Witzenrath M, Schaefer L, Markart P. Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury. Am J Respir Crit Care Med. 2017 07 15; 196(2):186-199.

View in: PubMed
Pepe J, Bielory L. New hope for those with hereditary angioedema. Nursing. 2012 Apr; 42(4):43-6.

View in: PubMed
Parish LC. Hereditary angioedema: diagnosis and management-a perspective for the dermatologist. J Am Acad Dermatol. 2011 Oct; 65(4):843-850.

View in: PubMed
Breitbart SI, Bielory L. Acquired angioedema: Autoantibody associations and C1q utility as a diagnostic tool. Allergy Asthma Proc. 2010 Sep-Oct; 31(5):428-34.

View in: PubMed
Zuraw BL, Busse PJ, White M, Jacobs J, Lumry W, Baker J, Craig T, Grant JA, Hurewitz D, Bielory L, Cartwright WE, Koleilat M, Ryan W, Schaefer O, Manning M, Patel P, Bernstein JA, Friedman RA, Wilkinson R, Tanner D, Kohler G, Gunther G, Levy R, McClellan J, Redhead J, Guss D, Heyman E, Blumenstein BA, Kalfus I, Frank MM. Nanofiltered C1 inhibitor concentrate for treatment of hereditary angioedema. N Engl J Med. 2010 Aug 05; 363(6):513-22.

View in: PubMed
Nagy N, Grattan CE, McGrath JA. New insights into hereditary angio-oedema: Molecular diagnosis and therapy. Australas J Dermatol. 2010 Aug; 51(3):157-62.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement