"Clusterin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly conserved heterodimeric glycoprotein that is differentially expressed during many severe physiological disturbance states such as CANCER; APOPTOSIS; and various NEUROLOGICAL DISORDERS. Clusterin is ubiquitously expressed and appears to function as a secreted MOLECULAR CHAPERONE.
| Descriptor ID |
D051152
|
| MeSH Number(s) |
D12.776.395.207 D12.776.580.215
|
| Concept/Terms |
Clusterin- Clusterin
- SGP-2 Protein
- SGP 2 Protein
- Apolipoprotein J
- Complement Lysis Inhibitor
- Complement-Associated Protein SP-40,40
- Complement Associated Protein SP 40,40
- SP-40,40, Complement-Associated Protein
- Sulfated Glycoprotein 2
- Sulfated Glycoprotein-2
- Ionizing Radiation-Induced Protein-8
- Ionizing Radiation Induced Protein 8
- Radiation-Induced Protein-8, Ionizing
- XIP8 Protein
- X-Ray-Inducible Protein 8
- X Ray Inducible Protein 8
- Testosterone-Repressed Prostate Message-2 Protein
- Testosterone Repressed Prostate Message 2 Protein
- ApoJ Protein
- TRPM-2 Protein
- TRPM 2 Protein
- MAC393 Antigen
- SP 40,40 Protein
|
Below are MeSH descriptors whose meaning is more general than "Clusterin".
Below are MeSH descriptors whose meaning is more specific than "Clusterin".
This graph shows the total number of publications written about "Clusterin" by people in this website by year, and whether "Clusterin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clusterin" by people in Profiles.
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El-Darzi N, Mast N, Li Y, Dailey B, Kang M, Rhee DJ, Pikuleva IA. The normalizing effects of the CYP46A1 activator efavirenz on retinal sterol levels and risk factors for glaucoma in Apoj-/-?mice. Cell Mol Life Sci. 2023 Jul 01; 80(7):194.
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Griffiths GS, Galileo DS, Aravindan RG, Martin-DeLeon PA. Clusterin facilitates exchange of glycosyl phosphatidylinositol-linked SPAM1 between reproductive luminal fluids and mouse and human sperm membranes. Biol Reprod. 2009 Sep; 81(3):562-70.
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Mocchegiani E, Giacconi R, Cipriano C, Costarelli L, Muti E, Tesei S, Giuli C, Papa R, Marcellini F, Mariani E, Rink L, Herbein G, Varin A, Fulop T, Monti D, Jajte J, Dedoussis G, Gonos ES, Trougakos IP, Malavolta M. Zinc, metallothioneins, and longevity--effect of zinc supplementation: zincage study. Ann N Y Acad Sci. 2007 Nov; 1119:129-46.
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Lakshman R, Tsutsumi M, Ghosh P, Takase S, Anni H, Nikolaeva O, Israel Y, Anton RF, Lesch OM, Helender A, Eriksson G, Jeppson JO, Marmillot P, Rao MN. Alcohol biomarkers: clinical significance and biochemical basis. Alcohol Clin Exp Res. 2001 May; 25(5 Suppl ISBRA):67S-70S.
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Cervellera M, Raschella G, Santilli G, Tanno B, Ventura A, Mancini C, Sevignani C, Calabretta B, Sala A. Direct transactivation of the anti-apoptotic gene apolipoprotein J (clusterin) by B-MYB. J Biol Chem. 2000 Jul 14; 275(28):21055-60.