James Mitroka

TitleAdjunct Faculty
InstitutionPhiladelphia University
DepartmentUndergraduate Programs
Address3243 School House Lane
Philadelphia PA 19144
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mitroka JG, Harrington C, DellaVecchia MJ. A multiyear comparison of flipped- vs. lecture-based teaching on student success in a pharmaceutical science class. Curr Pharm Teach Learn. 2020 01; 12(1):84-87. PMID: 31843170.
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    2. Harrison DJ, Mitroka JG. Defining reality: the potential role of pharmacists in assessing the impact of progesterone receptor modulators and misoprostol in reproductive health. Ann Pharmacother. 2011 Jan; 45(1):115-9. PMID: 21177418.
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    3. Zhang D, He K, Raghavan N, Wang L, Mitroka J, Maxwell BD, Knabb RM, Frost C, Schuster A, Hao F, Gu Z, Humphreys WG, Grossman SJ. Comparative metabolism of 14C-labeled apixaban in mice, rats, rabbits, dogs, and humans. Drug Metab Dispos. 2009 Aug; 37(8):1738-48. PMID: 19420130.
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    4. Drexler DM, Garrett TJ, Cantone JL, Diters RW, Mitroka JG, Prieto Conaway MC, Adams SP, Yost RA, Sanders M. Utility of imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization (MALDI) on an ion trap mass spectrometer in the analysis of drugs and metabolites in biological tissues. J Pharmacol Toxicol Methods. 2007 May-Jun; 55(3):279-88. PMID: 17222568.
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    5. Zhang D, Hanson R, Roongta V, Dischino DD, Gao Q, Sloan CP, Polson C, Keavy D, Zheng M, Mitroka J, Yeola S. In vitro and in vivo metabolism of a gamma-secretase inhibitor BMS-299897 and generation of active metabolites in milligram quantities with a microbial bioreactor. Curr Drug Metab. 2006 Dec; 7(8):883-96. PMID: 17168689.
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    6. Van Vleet TR, White MR, Sanderson TP, Cohen SM, Cano M, Arnold LL, Waites CR, Schilling BE, Mitroka J, Dominick MA. Subchronic urinary bladder effects of muraglitazar in male rats. Toxicol Sci. 2007 Mar; 96(1):58-71. PMID: 17132713.
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    7. Zhang D, Wang L, Raghavan N, Zhang H, Li W, Cheng PT, Yao M, Zhang L, Zhu M, Bonacorsi S, Yeola S, Mitroka J, Hariharan N, Hosagrahara V, Chandrasena G, Shyu WC, Humphreys WG. Comparative metabolism of radiolabeled muraglitazar in animals and humans by quantitative and qualitative metabolite profiling. Drug Metab Dispos. 2007 Jan; 35(1):150-67. PMID: 17062777.
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    8. Wait JC, Vaccharajani N, Mitroka J, Jemal M, Khan S, Bonacorsi SJ, Rinehart JK, Iyer RA. Metabolism of [14C]gemopatrilat after oral administration to rats, dogs, and humans. Drug Metab Dispos. 2006 Jun; 34(6):961-70. PMID: 16540589.
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    9. Zhu M, Zhao W, Vazquez N, Mitroka JG. Analysis of low level radioactive metabolites in biological fluids using high-performance liquid chromatography with microplate scintillation counting: method validation and application. J Pharm Biomed Anal. 2005 Sep 01; 39(1-2):233-45. PMID: 15899570.
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    10. Zhu M, Zhao W, Jimenez H, Zhang D, Yeola S, Dai R, Vachharajani N, Mitroka J. Cytochrome P450 3A-mediated metabolism of buspirone in human liver microsomes. Drug Metab Dispos. 2005 Apr; 33(4):500-7. PMID: 15640381.
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    11. Zhang D, Krishna R, Wang L, Zeng J, Mitroka J, Dai R, Narasimhan N, Reeves RA, Srinivas NR, Klunk LJ. Metabolism, pharmacokinetics, and protein covalent binding of radiolabeled MaxiPost (BMS-204352) in humans. Drug Metab Dispos. 2005 Jan; 33(1):83-93. PMID: 15502007.
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    12. Zhang D, Zhao W, Roongta VA, Mitroka JG, Klunk LJ, Zhu M. Amide N-glucuronidation of MaxiPost catalyzed by UDP-glucuronosyltransferase 2B7 in humans. Drug Metab Dispos. 2004 May; 32(5):545-51. PMID: 15100177.
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    13. Zhang D, Ogan M, Gedamke R, Roongta V, Dai R, Zhu M, Rinehart JK, Klunk L, Mitroka J. Protein covalent binding of maxipost through a cytochrome P450-mediated ortho-quinone methide intermediate in rats. Drug Metab Dispos. 2003 Jul; 31(7):837-45. PMID: 12814959.
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    14. Iyer RA, Malhotra B, Khan S, Mitroka J, Bonacorsi S, Waller SC, Rinehart JK, Kripalani K. Comparative biotransformation of radiolabeled [(14)C]omapatrilat and stable-labeled [(13)C(2)]omapatrilat after oral administration to rats, dogs, and humans. Drug Metab Dispos. 2003 Jan; 31(1):67-75. PMID: 12485955.
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    15. Malhotra BK, Iyer RA, Soucek KM, Behr D, Liao WC, Mitroka JG, Kaul S, Cohen MB, Knupp CA. Oral bioavailability and disposition of [14C]omapatrilat in healthy subjects. J Clin Pharmacol. 2001 Aug; 41(8):833-41. PMID: 11504270.
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    16. Iyer RA, Mitroka J, Malhotra B, Bonacorsi S, Waller SC, Rinehart JK, Roongta VA, Kripalani K. Metabolism of [(14)C]omapatrilat, a sulfhydryl-containing vasopeptidase inhibitor in humans. Drug Metab Dispos. 2001 Jan; 29(1):60-9. PMID: 11124231.
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    17. Dockens RC, Santone KS, Mitroka JG, Morrison RA, Jemal M, Greene DS, Barbhaiya RH. Disposition of radiolabeled ifetroban in rats, dogs, monkeys, and humans. Drug Metab Dispos. 2000 Aug; 28(8):973-80. PMID: 10901709.
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    18. Grover GJ, Parham CS, Whigan DB, Mitroka JG. BMS-180448, a novel glyburide-reversible cardioprotective agent, enhances postischemic recovery of contractile function in dogs. J Pharmacol Exp Ther. 1996 Feb; 276(2):380-7. PMID: 8632300.
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    19. Lan SJ, Scanlan LM, Mitroka J, Weinstein SH, Lutsky BN, Free CA, Wojnar RJ, Millonig RC, Migdalof BH. Rapid metabolic inactivation of tipredane, a structurally novel topical steroid. J Steroid Biochem. 1988 Nov; 31(5):825-34. PMID: 3199821.
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