"GRB10 Adaptor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A binding partner for several RECEPTOR PROTEIN-TYROSINE KINASES, including INSULIN RECEPTOR and INSULIN-LIKE GROWTH FACTOR RECEPTOR. It contains a C-terminal SH2 DOMAIN and mediates various SIGNAL TRANSDUCTION pathways.
| Descriptor ID |
D051383
|
| MeSH Number(s) |
D12.644.360.024.300 D12.776.157.057.039 D12.776.476.024.380
|
| Concept/Terms |
GRB10 Adaptor Protein- GRB10 Adaptor Protein
- Maternally Expressed Gene 1 Protein
- GRB10 Protein
- Growth Factor Receptor-Bound Protein 10
- Growth Factor Receptor Bound Protein 10
|
Below are MeSH descriptors whose meaning is more general than "GRB10 Adaptor Protein".
Below are MeSH descriptors whose meaning is more specific than "GRB10 Adaptor Protein".
This graph shows the total number of publications written about "GRB10 Adaptor Protein" by people in this website by year, and whether "GRB10 Adaptor Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "GRB10 Adaptor Protein" by people in Profiles.
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Monami G, Emiliozzi V, Morrione A. Grb10/Nedd4-mediated multiubiquitination of the insulin-like growth factor receptor regulates receptor internalization. J Cell Physiol. 2008 Aug; 216(2):426-37.
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Zhang Z, Kostetskii I, Moss SB, Jones BH, Ho C, Wang H, Kishida T, Gerton GL, Radice GL, Strauss JF. Haploinsufficiency for the murine orthologue of Chlamydomonas PF20 disrupts spermatogenesis. Proc Natl Acad Sci U S A. 2004 Aug 31; 101(35):12946-51.
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Morrione A. Grb10 adapter protein as regulator of insulin-like growth factor receptor signaling. J Cell Physiol. 2003 Dec; 197(3):307-11.
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Vecchione A, Marchese A, Henry P, Rotin D, Morrione A. The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor. Mol Cell Biol. 2003 May; 23(9):3363-72.