X-Linked Inhibitor of Apoptosis Protein
"X-Linked Inhibitor of Apoptosis Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inhibitor of apoptosis protein that is translated by a rare cap-independent mechanism. It blocks caspase-mediated cellular destruction by inhibiting CASPASE 3; CASPASE 7; and CASPASE 9.
| Descriptor ID |
D051636
|
| MeSH Number(s) |
D08.811.464.938.750.210.750 D12.644.360.075.437.750 D12.776.476.075.437.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "X-Linked Inhibitor of Apoptosis Protein".
Below are MeSH descriptors whose meaning is more specific than "X-Linked Inhibitor of Apoptosis Protein".
This graph shows the total number of publications written about "X-Linked Inhibitor of Apoptosis Protein" by people in this website by year, and whether "X-Linked Inhibitor of Apoptosis Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "X-Linked Inhibitor of Apoptosis Protein" by people in Profiles.
-
Dogan T, Harms GS, Hekman M, Karreman C, Oberoi TK, Alnemri ES, Rapp UR, Rajalingam K. X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility. Nat Cell Biol. 2008 Dec; 10(12):1447-55.
-
Liu HR, Gao E, Hu A, Tao L, Qu Y, Most P, Koch WJ, Christopher TA, Lopez BL, Alnemri ES, Zervos AS, Ma XL. Role of Omi/HtrA2 in apoptotic cell death after myocardial ischemia and reperfusion. Circulation. 2005 Jan 4; 111(1):90-6.
-
Srinivasula SM, Gupta S, Datta P, Zhang Z, Hegde R, Cheong N, Fernandes-Alnemri T, Alnemri ES. Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2. J Biol Chem. 2003 Aug 22; 278(34):31469-72.
-
Jia L, Patwari Y, Kelsey SM, Srinivasula SM, Agrawal SG, Alnemri ES, Newland AC. Role of Smac in human leukaemic cell apoptosis and proliferation. Oncogene. 2003 Mar 20; 22(11):1589-99.
-
Shiozaki EN, Chai J, Rigotti DJ, Riedl SJ, Li P, Srinivasula SM, Alnemri ES, Fairman R, Shi Y. Mechanism of XIAP-mediated inhibition of caspase-9. Mol Cell. 2003 Feb; 11(2):519-27.