"Sp3 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specificity protein transcription factor that contains three C-terminal CYS2-HIS2 ZINC FINGERS. It regulates expression of a variety of genes including VASCULAR ENDOTHELIAL GROWTH FACTOR and CYCLIN-DEPENDENT KINASE INHIBITOR P27.
| Descriptor ID |
D051705
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| MeSH Number(s) |
D12.776.260.522.750.750 D12.776.930.375.750.750
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sp3 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "Sp3 Transcription Factor".
This graph shows the total number of publications written about "Sp3 Transcription Factor" by people in this website by year, and whether "Sp3 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 2 | 1 | 3 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sp3 Transcription Factor" by people in Profiles.
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Kim JI, Urban M, Young GD, Eto M. Reciprocal regulation controlling the expression of CPI-17, a specific inhibitor protein for the myosin light chain phosphatase in vascular smooth muscle cells. Am J Physiol Cell Physiol. 2012 Jul 1; 303(1):C58-68.
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Kypriotou M, Beauchef G, Chadjichristos C, Widom R, Renard E, Jimenez SA, Korn J, Maquart FX, Oddos T, Von Stetten O, Pujol JP, Galéra P. Human collagen Krox up-regulates type I collagen expression in normal and scleroderma fibroblasts through interaction with Sp1 and Sp3 transcription factors. J Biol Chem. 2007 Nov 2; 282(44):32000-14.
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Yao D, Taguchi T, Matsumura T, Pestell R, Edelstein D, Giardino I, Suske G, Rabbani N, Thornalley PJ, Sarthy VP, Hammes HP, Brownlee M. High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A. J Biol Chem. 2007 Oct 19; 282(42):31038-45.
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Tone Y, Kojima Y, Furuuchi K, Brady M, Yashiro-Ohtani Y, Tykocinski ML, Tone M. OX40 gene expression is up-regulated by chromatin remodeling in its promoter region containing Sp1/Sp3, YY1, and NF-kappa B binding sites. J Immunol. 2007 Aug 1; 179(3):1760-7.
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Jiang Q, Matsuzaki Y, Li K, Uitto J. Transcriptional regulation and characterization of the promoter region of the human ABCC6 gene. J Invest Dermatol. 2006 Feb; 126(2):325-35.
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Yao D, Taguchi T, Matsumura T, Pestell R, Edelstein D, Giardino I, Suske G, Ahmed N, Thornalley PJ, Sarthy VP, Hammes HP, Brownlee M. Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription. Cell. 2006 Jan 27; 124(2):275-86.
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Castoldi M, Chu ML. Structural and functional characterization of the human and mouse fibulin-1 gene promoters: role of Sp1 and Sp3. Biochem J. 2002 Feb 15; 362(Pt 1):41-50.
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Lee RJ, Albanese C, Fu M, D'Amico M, Lin B, Watanabe G, Haines GK, Siegel PM, Hung MC, Yarden Y, Horowitz JM, Muller WJ, Pestell RG. Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway. Mol Cell Biol. 2000 Jan; 20(2):672-83.
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Harrington MA, Konicek B, Song A, Xia XL, Fredericks WJ, Rauscher FJ. Inhibition of colony-stimulating factor-1 promoter activity by the product of the Wilms' tumor locus. J Biol Chem. 1993 Oct 5; 268(28):21271-5.