Microphthalmia-Associated Transcription Factor
"Microphthalmia-Associated Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic helix-loop-helix leucine zipper transcription factor that regulates the CELL DIFFERENTIATION and development of a variety of cell types including MELANOCYTES; OSTEOCLASTS; and RETINAL PIGMENT EPITHELIUM. Mutations in MITF protein have been associated with OSTEOPETROSIS and WAARDENBURG SYNDROME.
| Descriptor ID |
D051739
|
| MeSH Number(s) |
D12.776.260.103.500.500 D12.776.260.108.092.500 D12.776.930.125.500.500 D12.776.930.127.092.500
|
| Concept/Terms |
Microphthalmia-Associated Transcription Factor- Microphthalmia-Associated Transcription Factor
- Microphthalmia Associated Transcription Factor
- Transcription Factor, Microphthalmia-Associated
- MITF Transcription Factor
- Transcription Factor Microphthalmia
- Microphthalmia, Transcription Factor
- MITF Protein
|
Below are MeSH descriptors whose meaning is more general than "Microphthalmia-Associated Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "Microphthalmia-Associated Transcription Factor".
This graph shows the total number of publications written about "Microphthalmia-Associated Transcription Factor" by people in this website by year, and whether "Microphthalmia-Associated Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Microphthalmia-Associated Transcription Factor" by people in Profiles.
-
Shields JA, Eagle RC, Dutton J, Ehya H, Shields CL. Adenocarcinoma of the retinal pigment epithelium: clinicopathologic correlation with paradoxical immunohistochemical findings. JAMA Ophthalmol. 2014 Oct; 132(10):1249-52.
-
Adijanto J, Castorino JJ, Wang ZX, Maminishkis A, Grunwald GB, Philp NJ. Microphthalmia-associated transcription factor (MITF) promotes differentiation of human retinal pigment epithelium (RPE) by regulating microRNAs-204/211 expression. J Biol Chem. 2012 Jun 8; 287(24):20491-503.
-
Pierrat MJ, Marsaud V, Mauviel A, Javelaud D. Expression of microphthalmia-associated transcription factor (MITF), which is critical for melanoma progression, is inhibited by both transcription factor GLI2 and transforming growth factor-?. J Biol Chem. 2012 May 25; 287(22):17996-8004.
-
Aplin AE. Axl of evil? J Invest Dermatol. 2011 Dec; 131(12):2343-5.
-
Javelaud D, Alexaki VI, Pierrat MJ, Hoek KS, Dennler S, Van Kempen L, Bertolotto C, Ballotti R, Saule S, Delmas V, Mauviel A. GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells. Pigment Cell Melanoma Res. 2011 Oct; 24(5):932-43.
-
Ramos RY, Haupt HM, Kanetsky PA, Donthineni-Rao R, Arenas-Elliott C, Lackman RD, Martin AM. Giant cell tumors: inquiry into immunohistochemical expression of CD117 (c-Kit), microphthalmia transcription factor, tartrate-resistant acid phosphatase, and HAM-56. Arch Pathol Lab Med. 2005 Mar; 129(3):360-5.