Nuclear Receptor Coactivator 1
"Nuclear Receptor Coactivator 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and THYROID HORMONE RECEPTORS. It contains a HISTONE ACETYLTRANSFRASE activity that may play a role in the transcriptional activation of CHROMATIN regions.
| Descriptor ID |
D056920
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| MeSH Number(s) |
D08.811.913.050.134.415.500.100 D12.644.360.024.314.100 D12.776.157.057.080.100 D12.776.260.103.782 D12.776.476.024.394.100 D12.776.660.675.100 D12.776.930.125.500.625 D12.776.930.617.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Coactivator 1".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Coactivator 1".
This graph shows the total number of publications written about "Nuclear Receptor Coactivator 1" by people in this website by year, and whether "Nuclear Receptor Coactivator 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Coactivator 1" by people in Profiles.
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Hartmaier RJ, Richter AS, Gillihan RM, Sallit JZ, McGuire SE, Wang J, Lee AV, Osborne CK, O'Malley BW, Brown PH, Xu J, Skaar TC, Philips S, Rae JM, Azzouz F, Li L, Hayden J, Henry NL, Nguyen AT, Stearns V, Hayes DF, Flockhart DA, Oesterreich S. A SNP in steroid receptor coactivator-1 disrupts a GSK3? phosphorylation site and is associated with altered tamoxifen response in bone. Mol Endocrinol. 2012 Feb; 26(2):220-7.
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Dennler S, Pendaries V, Tacheau C, Costas MA, Mauviel A, Verrecchia F. The steroid receptor co-activator-1 (SRC-1) potentiates TGF-beta/Smad signaling: role of p300/CBP. Oncogene. 2005 Mar 10; 24(11):1936-45.
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Ghadimi BM, Schr?ck E, Walker RL, Wangsa D, Jauho A, Meltzer PS, Ried T. Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas. Am J Pathol. 1999 Feb; 154(2):525-36.
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Bautista S, Vall?s H, Walker RL, Anzick S, Zeillinger R, Meltzer P, Theillet C. In breast cancer, amplification of the steroid receptor coactivator gene AIB1 is correlated with estrogen and progesterone receptor positivity. Clin Cancer Res. 1998 Dec; 4(12):2925-9.
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Anzick SL, Kononen J, Walker RL, Azorsa DO, Tanner MM, Guan XY, Sauter G, Kallioniemi OP, Trent JM, Meltzer PS. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science. 1997 Aug 15; 277(5328):965-8.