Smad2 Protein

"Smad2 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A receptor-regulated smad protein that undergoes PHOSPHORYLATION by ACTIVIN RECEPTORS, TYPE I. It regulates TRANSFORMING GROWTH FACTOR BETA and ACTIVIN signaling.

Descriptor ID	D051899
MeSH Number(s)	D12.644.360.024.334.500.200 D12.776.157.057.170.500.200 D12.776.476.024.428.500.200 D12.776.744.741.750 D12.776.930.806.500.200
Concept/Terms	Smad2 Protein Smad2 Protein MAD-Related 2 Protein MAD Related 2 Protein MADR2 Protein

Below are MeSH descriptors whose meaning is more general than "Smad2 Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
Smad Proteins [D12.644.360.024.334]
Smad Proteins, Receptor-Regulated [D12.644.360.024.334.500]
Smad2 Protein [D12.644.360.024.334.500.200]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
Smad Proteins [D12.776.157.057.170]
Smad Proteins, Receptor-Regulated [D12.776.157.057.170.500]
Smad2 Protein [D12.776.157.057.170.500.200]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
Smad Proteins [D12.776.476.024.428]
Smad Proteins, Receptor-Regulated [D12.776.476.024.428.500]
Smad2 Protein [D12.776.476.024.428.500.200]
Phosphoproteins [D12.776.744]
Smad Proteins, Receptor-Regulated [D12.776.744.741]
Smad2 Protein [D12.776.744.741.750]
Transcription Factors [D12.776.930]
Smad Proteins [D12.776.930.806]
Smad Proteins, Receptor-Regulated [D12.776.930.806.500]
Smad2 Protein [D12.776.930.806.500.200]

Below are MeSH descriptors whose meaning is related to "Smad2 Protein".

Below are MeSH descriptors whose meaning is more specific than "Smad2 Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Smad2 Protein" by people in this website by year, and whether "Smad2 Protein" was a major or minor topic of these publications.

Bar chart showing 18 publications over 13 distinct years, with a maximum of 3 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	0	1	1
2006	0	2	2
2007	1	0	1
2008	0	1	1
2010	0	2	2
2011	0	1	1
2012	1	0	1
2013	0	2	2
2014	0	3	3
2016	1	0	1
2017	0	1	1
2022	0	1	1

Below are the most recent publications written about "Smad2 Protein" by people in Profiles.

Bertrand-Chapel A, Caligaris C, Fenouil T, Savary C, Aires S, Martel S, Huched? P, Chassot C, Chauvet V, Cardot-Ruffino V, Morel AP, Subtil F, Mohkam K, Mabrut JY, Tonon L, Viari A, Cassier P, Hervieu V, Castets M, Mauviel A, Sentis S, Bartholin L. SMAD2/3 mediate oncogenic effects of TGF-? in the absence of SMAD4. Commun Biol. 2022 10 07; 5(1):1068.

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Zhang Y, O'Leary MN, Peri S, Wang M, Zha J, Melov S, Kappes DJ, Feng Q, Rhodes J, Amieux PS, Morris DR, Kennedy BK, Wiest DL. Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Cell Rep. 2017 01 10; 18(2):545-556.

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Wang W, Song B, Anbarchian T, Shirazyan A, Sadik JE, Lyons KM. Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. PLoS Genet. 2016 Oct; 12(10):e1006352.

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Khan S, Joyce J, Margulies KB, Tsuda T. Enhanced bioactive myocardial transforming growth factor-? in advanced human heart failure. Circ J. 2014; 78(11):2711-8.

View in: PubMed
Stephen TL, Rutkowski MR, Allegrezza MJ, Perales-Puchalt A, Tesone AJ, Svoronos N, Nguyen JM, Sarmin F, Borowsky ME, Tchou J, Conejo-Garcia JR. Transforming growth factor ?-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression. Immunity. 2014 Sep 18; 41(3):427-439.

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Kern G, Mair SM, Noppert SJ, Jennings P, Schramek H, Rudnicki M, Mueller GA, Mayer G, Koppelstaetter C. Tacrolimus increases Nox4 expression in human renal fibroblasts and induces fibrosis-related genes by aberrant TGF-beta receptor signalling. PLoS One. 2014; 9(5):e96377.

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Hagler MA, Hadley TM, Zhang H, Mehra K, Roos CM, Schaff HV, Suri RM, Miller JD. TGF-? signalling and reactive oxygen species drive fibrosis and matrix remodelling in myxomatous mitral valves. Cardiovasc Res. 2013 Jul 01; 99(1):175-84.

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Abbas T, Mueller AC, Shibata E, Keaton M, Rossi M, Dutta A. CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration. Mol Cell. 2013 Mar 28; 49(6):1147-58.

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Miles FL, Tung NS, Aguiar AA, Kurtoglu S, Sikes RA. Increased TGF-ß1-mediated suppression of growth and motility in castrate-resistant prostate cancer cells is consistent with Smad2/3 signaling. Prostate. 2012 Sep 1; 72(12):1339-50.

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Pulina MV, Hou SY, Mittal A, Julich D, Whittaker CA, Holley SA, Hynes RO, Astrof S. Essential roles of fibronectin in the development of the left-right embryonic body plan. Dev Biol. 2011 Jun 15; 354(2):208-20.

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