Bone Morphogenetic Proteins

"Bone Morphogenetic Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.

Descriptor ID	D019485
MeSH Number(s)	D12.644.276.954.200 D12.776.467.942.200 D23.529.942.200
Concept/Terms	Bone Morphogenetic Proteins Bone Morphogenetic Proteins Morphogenetic Proteins, Bone Bone Morphogenetic Protein Morphogenetic Protein, Bone

Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
TGF-beta Superfamily Proteins [D12.644.276.954]
Bone Morphogenetic Proteins [D12.644.276.954.200]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
TGF-beta Superfamily Proteins [D12.776.467.942]
Bone Morphogenetic Proteins [D12.776.467.942.200]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
TGF-beta Superfamily Proteins [D23.529.942]
Bone Morphogenetic Proteins [D23.529.942.200]

Below are MeSH descriptors whose meaning is related to "Bone Morphogenetic Proteins".

Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bone Morphogenetic Proteins" by people in this website by year, and whether "Bone Morphogenetic Proteins" was a major or minor topic of these publications.

Bar chart showing 118 publications over 27 distinct years, with a maximum of 12 publications in 2003 and 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	3	3
1997	3	0	3
1998	3	0	3
1999	2	0	2
2000	2	0	2
2001	3	4	7
2002	3	1	4
2003	10	2	12
2004	5	2	7
2005	8	0	8
2006	6	1	7
2007	6	1	7
2008	7	5	12
2009	4	2	6
2010	3	3	6
2011	2	0	2
2012	1	1	2
2013	1	2	3
2014	2	1	3
2016	3	4	7
2017	3	1	4
2018	1	0	1
2019	2	0	2
2020	1	0	1
2021	0	1	1
2023	2	0	2
2024	1	0	1

Below are the most recent publications written about "Bone Morphogenetic Proteins" by people in Profiles.

Ibrahim S, Michalopoulos GD, Flanigan P, Johnson SE, Katsos K, Sebastian AS, Freedman BA, Bydon M. Bone morphogenetic protein in subaxial cervical arthrodesis: a meta-analysis of 5828 patients. J Neurosurg Spine. 2024 08 01; 41(2):174-187.

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Lyons KM, Rosen V. Strengthening the case for BMP inhibition as a point of intervention for osteoarthritis. Osteoarthritis Cartilage. 2023 11; 31(11):1423-1424.

View in: PubMed
Bernatz JT, Fisher MWA, Pinter ZW, Sebastian AS. Controversies in Spine Surgery: Is i-Factor Superior to Bone Morphogenic Protein for Achieving Spine Fusion? Clin Spine Surg. 2023 07 01; 36(6):224-226.

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Castro-Mollo M, Gera S, Ruiz-Martinez M, Feola M, Gumerova A, Planoutene M, Clementelli C, Sangkhae V, Casu C, Kim SM, Ostland V, Han H, Nemeth E, Fleming R, Rivella S, Lizneva D, Yuen T, Zaidi M, Ginzburg Y. The hepcidin regulator erythroferrone is a new member of the erythropoiesis-iron-bone circuitry. Elife. 2021 05 18; 10.

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Wang W, Rigueur D, Lyons KM. TGF? as a gatekeeper of BMP action in the developing growth plate. Bone. 2020 08; 137:115439.

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Dettori JR, Chapman JR, DeVine JG, McGuire RA, Junge MR, Norvell DC. Longer follow-up continues to reveal no increased risk of cancer with the use of recombinant human bone morphogenetic protein in spine fusion. Spine J. 2019 10; 19(10):1640-1647.

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Lyons KM, Rosen V. BMPs, TGF?, and border security at the interzone. Curr Top Dev Biol. 2019; 133:153-170.

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Pons M, Koniaris LG, Moe SM, Gutierrez JC, Esquela-Kerscher A, Zimmers TA. GDF11 induces kidney fibrosis, renal cell epithelial-to-mesenchymal transition, and kidney dysfunction and failure. Surgery. 2018 08; 164(2):262-273.

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Garg S, McCarthy JJ, Goodwin R, Kolmodin J, Sankar WN, Franklin C, Armstrong D, Fryzel D, Hassenbein S, Meder C. Complication Rates After Bone Morphogenetic Protein (BMP) Use in Orthopaedic Surgery in Children: A Concise Multicenter Retrospective Cohort Study. J Pediatr Orthop. 2017 Sep; 37(6):e375-e378.

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Zimmers TA, Jiang Y, Wang M, Liang TW, Rupert JE, Au ED, Marino FE, Couch ME, Koniaris LG. Exogenous GDF11 induces cardiac and skeletal muscle dysfunction and wasting. Basic Res Cardiol. 2017 07; 112(4):48.

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