Bone Morphogenetic Proteins
"Bone Morphogenetic Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.
| Descriptor ID |
D019485
|
| MeSH Number(s) |
D12.644.276.954.200 D12.776.467.942.200 D23.529.942.200
|
| Concept/Terms |
Bone Morphogenetic Proteins- Bone Morphogenetic Proteins
- Morphogenetic Proteins, Bone
- Bone Morphogenetic Protein
- Morphogenetic Protein, Bone
|
Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Proteins".
Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Proteins".
This graph shows the total number of publications written about "Bone Morphogenetic Proteins" by people in this website by year, and whether "Bone Morphogenetic Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1997 | 2 | 0 | 2 |
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 2 | 0 | 2 |
| 2001 | 2 | 3 | 5 |
| 2002 | 2 | 1 | 3 |
| 2003 | 7 | 1 | 8 |
| 2004 | 5 | 2 | 7 |
| 2005 | 6 | 0 | 6 |
| 2006 | 5 | 1 | 6 |
| 2007 | 4 | 0 | 4 |
| 2008 | 4 | 3 | 7 |
| 2009 | 4 | 1 | 5 |
| 2010 | 3 | 2 | 5 |
| 2011 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 3 | 4 |
| 2017 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Bone Morphogenetic Proteins" by people in Profiles.
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Lyons KM, Rosen V. Strengthening the case for BMP inhibition as a point of intervention for osteoarthritis. Osteoarthritis Cartilage. 2023 11; 31(11):1423-1424.
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Bernatz JT, Fisher MWA, Pinter ZW, Sebastian AS. Controversies in Spine Surgery: Is i-Factor Superior to Bone Morphogenic Protein for Achieving Spine Fusion? Clin Spine Surg. 2023 07 01; 36(6):224-226.
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Wang W, Rigueur D, Lyons KM. TGF? as a gatekeeper of BMP action in the developing growth plate. Bone. 2020 08; 137:115439.
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Dettori JR, Chapman JR, DeVine JG, McGuire RA, Junge MR, Norvell DC. Longer follow-up continues to reveal no increased risk of cancer with the use of recombinant human bone morphogenetic protein in spine fusion. Spine J. 2019 10; 19(10):1640-1647.
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Lyons KM, Rosen V. BMPs, TGF?, and border security at the interzone. Curr Top Dev Biol. 2019; 133:153-170.
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Pan H, Zhang H, Abraham P, Komatsu Y, Lyons K, Kaartinen V, Mishina Y. BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development. Dev Biol. 2017 09 01; 429(1):260-270.
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Rosenbloom J, Macarak E, Piera-Velazquez S, Jimenez SA. Human Fibrotic Diseases: Current Challenges in Fibrosis Research. Methods Mol Biol. 2017; 1627:1-23.
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Heo SJ, Han WM, Szczesny SE, Cosgrove BD, Elliott DM, Lee DA, Duncan RL, Mauck RL. Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells. Biophys J. 2016 Aug 23; 111(4):864-874.
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Schafer MJ, Atkinson EJ, Vanderboom PM, Kotajarvi B, White TA, Moore MM, Bruce CJ, Greason KL, Suri RM, Khosla S, Miller JD, Bergen HR, LeBrasseur NK. Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease. Cell Metab. 2016 Jun 14; 23(6):1207-1215.
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Shi C, Iura A, Terajima M, Liu F, Lyons K, Pan H, Zhang H, Yamauchi M, Mishina Y, Sun H. Deletion of BMP receptor type IB decreased bone mass in association with compromised osteoblastic differentiation of bone marrow mesenchymal progenitors. Sci Rep. 2016 Apr 06; 6:24256.