Cyclooxygenase 2 Inhibitors

"Cyclooxygenase 2 Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subclass of cyclooxygenase inhibitors with specificity for CYCLOOXYGENASE-2.

Descriptor ID	D052246
MeSH Number(s)	D27.505.519.389.310.500 D27.505.696.663.850.014.040.500.500.500 D27.505.954.158.030.500.500 D27.505.954.329.030.500.500
Concept/Terms	Cyclooxygenase 2 Inhibitors Cyclooxygenase 2 Inhibitors Inhibitors, Cyclooxygenase 2 Cyclooxygenase-2 Inhibitors Inhibitors, Cyclooxygenase-2 Coxibs COX-2 Inhibitors COX 2 Inhibitors Inhibitors, COX-2 COX2 Inhibitors Inhibitors, COX2

Below are MeSH descriptors whose meaning is more general than "Cyclooxygenase 2 Inhibitors".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Enzyme Inhibitors [D27.505.519.389]
Cyclooxygenase Inhibitors [D27.505.519.389.310]
Cyclooxygenase 2 Inhibitors [D27.505.519.389.310.500]
Physiological Effects of Drugs [D27.505.696]
Peripheral Nervous System Agents [D27.505.696.663]
Sensory System Agents [D27.505.696.663.850]
Analgesics [D27.505.696.663.850.014]
Analgesics, Non-Narcotic [D27.505.696.663.850.014.040]
Anti-Inflammatory Agents, Non-Steroidal [D27.505.696.663.850.014.040.500]
Cyclooxygenase Inhibitors [D27.505.696.663.850.014.040.500.500]
Cyclooxygenase 2 Inhibitors [D27.505.696.663.850.014.040.500.500.500]
Therapeutic Uses [D27.505.954]
Anti-Inflammatory Agents [D27.505.954.158]
Anti-Inflammatory Agents, Non-Steroidal [D27.505.954.158.030]
Cyclooxygenase Inhibitors [D27.505.954.158.030.500]
Cyclooxygenase 2 Inhibitors [D27.505.954.158.030.500.500]
Antirheumatic Agents [D27.505.954.329]
Anti-Inflammatory Agents, Non-Steroidal [D27.505.954.329.030]
Cyclooxygenase Inhibitors [D27.505.954.329.030.500]
Cyclooxygenase 2 Inhibitors [D27.505.954.329.030.500.500]

Below are MeSH descriptors whose meaning is related to "Cyclooxygenase 2 Inhibitors".

Below are MeSH descriptors whose meaning is more specific than "Cyclooxygenase 2 Inhibitors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cyclooxygenase 2 Inhibitors" by people in this website by year, and whether "Cyclooxygenase 2 Inhibitors" was a major or minor topic of these publications.

Bar chart showing 52 publications over 17 distinct years, with a maximum of 7 publications in 2003 and 2007 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
2000	0	1	1
2001	0	2	2
2003	0	7	7
2004	0	2	2
2005	0	2	2
2006	2	2	4
2007	5	2	7
2008	3	3	6
2009	5	2	7
2010	3	2	5
2011	2	1	3
2012	0	1	1
2014	1	0	1
2015	1	0	1
2021	1	0	1
2022	0	1	1

Below are the most recent publications written about "Cyclooxygenase 2 Inhibitors" by people in Profiles.

Haffar A, Fillingham YA, Breckenridge L, Gursay D, Lonner JH. Meloxicam versus Celecoxib for Postoperative Analgesia after Total Knee Arthroplasty: Safety, Efficacy and Cost. J Am Acad Orthop Surg Glob Res Rev. 2022 04 05; 6(4).

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Meyerhardt JA, Shi Q, Fuchs CS, Meyer J, Niedzwiecki D, Zemla T, Kumthekar P, Guthrie KA, Couture F, Kuebler P, Bendell JC, Kumar P, Lewis D, Tan B, Bertagnolli M, Grothey A, Hochster HS, Goldberg RM, Venook A, Blanke C, O'Reilly EM, Shields AF. Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon Cancer: The CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial. JAMA. 2021 04 06; 325(13):1277-1286.

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Schwartz JI, Musser BJ, Tanaka WK, Taggart WV, Mehta A, Gottesdiener KM, Greenberg HE. Inhibition of prostacyclin and thromboxane biosynthesis in healthy volunteers by single and multiple doses of acetaminophen and indomethacin. Clin Pharmacol Drug Dev. 2015 09; 4(5):337-45.

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Ng K, Meyerhardt JA, Chan AT, Sato K, Chan JA, Niedzwiecki D, Saltz LB, Mayer RJ, Benson AB, Schaefer PL, Whittom R, Hantel A, Goldberg RM, Venook AP, Ogino S, Giovannucci EL, Fuchs CS. Aspirin and COX-2 inhibitor use in patients with stage III colon cancer. J Natl Cancer Inst. 2015 Jan; 107(1):345.

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Predina JD, Judy B, Fridlender ZG, Aliperti LA, Madajewski B, Kapoor V, Cheng G, Quatromoni J, Okusanya O, Singhal S. A positive-margin resection model recreates the postsurgical tumor microenvironment and is a reliable model for adjuvant therapy evaluation. Cancer Biol Ther. 2012 Jul; 13(9):745-55.

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Djavan B, Eastham J, Gomella L, Tombal B, Taneja S, Dianat SS, Kazzazi A, Shore N, Abrahamsson PA, Cheetham P, Moul J, Lepor H, Crawford ED. Testosterone in prostate cancer: the Bethesda consensus. BJU Int. 2012 Aug; 110(3):344-52.

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Wenner MM, Edwards DG, Ray CA, Rose WC, Gardner TJ, Stillabower M, Farquhar WB. Celecoxib does not alter cardiovascular and renal function during dietary salt loading. Clin Exp Pharmacol Physiol. 2011 Aug; 38(8):543-9.

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Parvizi J, Miller AG, Gandhi K. Multimodal pain management after total joint arthroplasty. J Bone Joint Surg Am. 2011 Jun 1; 93(11):1075-84.

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Zhu B, Bai R, Kennett MJ, Kang BH, Gonzalez FJ, Peters JM. Chemoprevention of chemically induced skin tumorigenesis by ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase 2. Mol Cancer Ther. 2010 Dec; 9(12):3267-77.

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Goldberg RM, Bertagnolli MM. VICTOR spoiled? J Clin Oncol. 2010 Oct 20; 28(30):4546-8.

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