"Gene Regulatory Networks" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.
| Descriptor ID |
D053263
|
| MeSH Number(s) |
G05.360.080.689.360
|
| Concept/Terms |
Gene Regulatory Networks- Gene Regulatory Networks
- Gene Regulatory Network
- Network, Gene Regulatory
- Networks, Gene Regulatory
- Regulatory Network, Gene
- Regulatory Networks, Gene
- Gene Networks
- Gene Network
- Network, Gene
- Networks, Gene
- Transcriptional Networks
- Network, Transcriptional
- Networks, Transcriptional
- Transcriptional Network
Gene Circuits- Gene Circuits
- Circuit, Gene
- Circuits, Gene
- Gene Circuit
Gene Modules- Gene Modules
- Module, Gene
- Modules, Gene
- Gene Module
|
Below are MeSH descriptors whose meaning is more general than "Gene Regulatory Networks".
Below are MeSH descriptors whose meaning is more specific than "Gene Regulatory Networks".
This graph shows the total number of publications written about "Gene Regulatory Networks" by people in this website by year, and whether "Gene Regulatory Networks" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 2 | 3 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 3 | 1 | 4 |
| 2015 | 1 | 3 | 4 |
| 2017 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Regulatory Networks" by people in Profiles.
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Mitra R, Adams CM, Eischen CM. Systematic lncRNA mapping to genome-wide co-essential modules uncovers cancer dependency on uncharacterized lncRNAs. Elife. 2022 06 13; 11.
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Peters LA, Perrigoue J, Mortha A, Iuga A, Song WM, Neiman EM, Llewellyn SR, Di Narzo A, Kidd BA, Telesco SE, Zhao Y, Stojmirovic A, Sendecki J, Shameer K, Miotto R, Losic B, Shah H, Lee E, Wang M, Faith JJ, Kasarskis A, Brodmerkel C, Curran M, Das A, Friedman JR, Fukui Y, Humphrey MB, Iritani BM, Sibinga N, Tarrant TK, Argmann C, Hao K, Roussos P, Zhu J, Zhang B, Dobrin R, Mayer LF, Schadt EE. A functional genomics predictive network model identifies regulators of inflammatory bowel disease. Nat Genet. 2017 Oct; 49(10):1437-1449.
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Jiang W, Mitra R, Lin CC, Wang Q, Cheng F, Zhao Z. Systematic dissection of dysregulated transcription factor-miRNA feed-forward loops across tumor types. Brief Bioinform. 2016 11; 17(6):996-1008.
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Lin CC, Mitra R, Cheng F, Zhao Z. A cross-cancer differential co-expression network reveals microRNA-regulated oncogenic functional modules. Mol Biosyst. 2015 Dec; 11(12):3244-52.
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Lin CC, Jiang W, Mitra R, Cheng F, Yu H, Zhao Z. Regulation rewiring analysis reveals mutual regulation between STAT1 and miR-155-5p in tumor immunosurveillance in seven major cancers. Sci Rep. 2015 Jul 09; 5:12063.
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Mitra R, Lin CC, Eischen CM, Bandyopadhyay S, Zhao Z. Concordant dysregulation of miR-5p and miR-3p arms of the same precursor microRNA may be a mechanism in inducing cell proliferation and tumorigenesis: a lung cancer study. RNA. 2015 Jun; 21(6):1055-65.
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Mitra R, Zhao Z. The oncogenic and prognostic potential of eight microRNAs identified by a synergetic regulatory network approach in lung cancer. Int J Comput Biol Drug Des. 2014; 7(4):384-93.
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Yu H, Mitra R, Yang J, Li Y, Zhao Z. Algorithms for network-based identification of differential regulators from transcriptome data: a systematic evaluation. Sci China Life Sci. 2014 Nov; 57(11):1090-102.
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Lin CC, Mitra R, Zhao Z. A tri-component conservation strategy reveals highly confident microRNA-mRNA interactions and evolution of microRNA regulatory networks. PLoS One. 2014; 9(7):e103142.
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Mitra R, Edmonds MD, Sun J, Zhao M, Yu H, Eischen CM, Zhao Z. Reproducible combinatorial regulatory networks elucidate novel oncogenic microRNAs in non-small cell lung cancer. RNA. 2014 Sep; 20(9):1356-68.