Models, Biological

"Models, Biological" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.

Descriptor ID	D008954
MeSH Number(s)	E05.599.395
Concept/Terms	Models, Biological Models, Biological Models, Biologic Biologic Model Biologic Models Model, Biologic Model, Biological Biological Model Biological Models

Below are MeSH descriptors whose meaning is more general than "Models, Biological".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Models, Theoretical [E05.599]
Models, Biological [E05.599.395]

Below are MeSH descriptors whose meaning is related to "Models, Biological".

Below are MeSH descriptors whose meaning is more specific than "Models, Biological".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Models, Biological" by people in this website by year, and whether "Models, Biological" was a major or minor topic of these publications.

Bar chart showing 436 publications over 28 distinct years, with a maximum of 39 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	1	2
1997	3	3	6
1998	1	8	9
1999	1	9	10
2000	2	3	5
2001	2	6	8
2002	6	6	12
2003	5	20	25
2004	1	16	17
2005	4	20	24
2006	5	20	25
2007	2	18	20
2008	8	27	35
2009	6	21	27
2010	10	29	39
2011	6	18	24
2012	8	9	17
2013	12	15	27
2014	6	15	21
2015	9	6	15
2016	2	7	9
2017	4	6	10
2018	7	6	13
2019	7	8	15
2020	5	3	8
2021	1	4	5
2022	0	1	1
2024	4	3	7

Below are the most recent publications written about "Models, Biological" by people in Profiles.

Fainsod A, Vadigepalli R. Rethinking retinoic acid self-regulation: A signaling robustness network approach. Curr Top Dev Biol. 2025; 161:113-141.

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Huestis MA, Smith WB, Leonowens C, Blanchard R, Viaccoz A, Spargo E, Miner NB, Yazar-Klosinski B. MDMA pharmacokinetics: A population and physiologically based pharmacokinetics model-informed analysis. CPT Pharmacometrics Syst Pharmacol. 2025 02; 14(2):376-388.

View in: PubMed
Kuchimanchi M, J?rgensen TL, Hanze E, Andr? T, Jain A, Berton D, Alsk?r O, Zub O, Oaknin A, Shahin MS, Koliadi A, Pothuri B, Krivak T, Pishchyk M, Segev Y, Backes FJ, Gennigens C, Bouberhan S, Zajic S, Melhem M, Buscema J. Population pharmacokinetics and exposure-response relationships of dostarlimab in primary advanced or recurrent endometrial cancer in part 1 of RUBY. Br J Clin Pharmacol. 2025 Mar; 91(3):841-855.

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George WT, Debopadhaya S, Stephen SJ, Botti BA, Burr DB, Vashishth D. Stress fracture of bone under physiological multiaxial cyclic loading: Activity-based predictive models. Bone. 2025 01; 190:117279.

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Shimonosono M, Morimoto M, Hirose W, Tomita Y, Matsuura N, Flashner S, Ebadi MS, Okayasu EH, Lee CY, Britton WR, Martin C, Wuertz BR, Parikh AS, Sachdeva UM, Ondrey FG, Atigadda VR, Elmets CA, Abrams JA, Muir AB, Klein-Szanto AJ, Weinberg KI, Momen-Heravi F, Nakagawa H. Modeling Epithelial Homeostasis and Perturbation in Three-Dimensional Human Esophageal Organoids. Biomolecules. 2024 09 05; 14(9).

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Sannala CKR, MacLean C, Larsen F, van Os S, Jadhav P, Shore N, Morgans AK, Okwuosa T, Gobburu J. A Model-Informed Drug Development Approach to Design a Phase 3 Trial of Teverelix Drug Product in Advanced Prostate Cancer Patients with Increased Cardiovascular Risk. Clin Pharmacol Drug Dev. 2024 08; 13(8):915-929.

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Qi Y, Chan ML, Mould DR, Larimore K, Fisheleva E, Cherukuri A, Day J, Savarirayan R, Irving M, Bacino CA, Hoover-Fong J, Ozono K, Mohnike K, Wilcox WR, Bober MB, Henshaw J. Development of a Weight-Band Dosing Approach for Vosoritide in Children with Achondroplasia Using a Population Pharmacokinetic Model. Clin Pharmacokinet. 2024 05; 63(5):707-719.

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Kolewe EL, Padhye S, Woodward IR, Wee J, Rahman T, Feng Y, Briddell JW, Fromen CA. Spatial aerosol deposition correlated to anatomic feature development in 6-year-old upper airway computational models. Comput Biol Med. 2022 10; 149:106058.

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Srivastava A, Ambr?sio DL, Tasak M, Gosavi U, G?nzl A. A distinct complex of PRP19-related and trypanosomatid-specific proteins is required for pre-mRNA splicing in trypanosomes. Nucleic Acids Res. 2021 12 16; 49(22):12929-12942.

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Andrews JM, Pyfrom SC, Schmidt JA, Koues OI, Kowalewski RA, Grams NR, Sun JJ, Berman LR, Duncavage EJ, Lee YS, Cashen AF, Oltz EM, Payton JE. Loss of synergistic transcriptional feedback loops drives diverse B-cell cancers. EBioMedicine. 2021 Sep; 71:103559.

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