Apoptotic Protease-Activating Factor 1

"Apoptotic Protease-Activating Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A CARD signaling adaptor protein characterized by an N-terminal CARD DOMAIN and C-terminal WD40 REPEATS. It plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY) and binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX which activates INITIATOR CASPASES such as CASPASE 9.

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This graph shows the total number of publications written about "Apoptotic Protease-Activating Factor 1" by people in this website by year, and whether "Apoptotic Protease-Activating Factor 1" was a major or minor topic of these publications.
Bar chart showing 16 publications over 6 distinct years, with a maximum of 7 publications in 2001
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