Myeloid Differentiation Factor 88
"Myeloid Differentiation Factor 88" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.
| Descriptor ID |
D053594
|
| MeSH Number(s) |
D12.644.360.024.311 D12.776.157.057.074 D12.776.476.024.390
|
| Concept/Terms |
Myeloid Differentiation Factor 88- Myeloid Differentiation Factor 88
- Toll-Like Receptor Signal Adaptor Protein MyD88
- Toll Like Receptor Signal Adaptor Protein MyD88
- MyD88 Protein
- TLR Signal Adaptor Protein MyD88
|
Below are MeSH descriptors whose meaning is more general than "Myeloid Differentiation Factor 88".
Below are MeSH descriptors whose meaning is more specific than "Myeloid Differentiation Factor 88".
This graph shows the total number of publications written about "Myeloid Differentiation Factor 88" by people in this website by year, and whether "Myeloid Differentiation Factor 88" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 2 | 0 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 1 | 3 |
| 2016 | 3 | 1 | 4 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myeloid Differentiation Factor 88" by people in Profiles.
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Schell SL, Soni C, Fasnacht MJ, Domeier PP, Cooper TK, Rahman ZSM. Mer Receptor Tyrosine Kinase Signaling Prevents Self-Ligand Sensing and Aberrant Selection in Germinal Centers. J Immunol. 2017 12 15; 199(12):4001-4015.
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Zhou H, Harberts E, Fishelevich R, Gaspari AA. TLR4 acts as a death receptor for ultraviolet radiation (UVR) through IRAK-independent and FADD-dependent pathway in macrophages. Exp Dermatol. 2016 12; 25(12):949-955.
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Tao Y, Zhang X, Markovic-Plese S. Toll-like receptor (TLR)7 and TLR9 agonists enhance interferon (IFN) beta-1a's immunoregulatory effects on B cells in patients with relapsing-remitting multiple sclerosis (RRMS). J Neuroimmunol. 2016 09 15; 298:181-8.
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Pulido JS, Raja H, Vile RG, Salomao DR, Viswanatha DS. Mighty MyD88 in Health and Disease. Retina. 2016 Mar; 36(3):429-31.
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Raja H, Salom?o DR, Viswanatha DS, Pulido JS. PREVALENCE OF MYD88 L265P MUTATION IN HISTOLOGICALLY PROVEN, DIFFUSE LARGE B-CELL VITREORETINAL LYMPHOMA. Retina. 2016 Mar; 36(3):624-8.
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Xu RH, Wong EB, Rubio D, Roscoe F, Ma X, Nair S, Remakus S, Schwendener R, John S, Shlomchik M, Sigal LJ. Sequential Activation of Two Pathogen-Sensing Pathways Required for Type I Interferon Expression and Resistance to an Acute DNA Virus Infection. Immunity. 2015 Dec 15; 43(6):1148-59.
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Pulido JS, Salomao DR, Frederick LA, Viswanatha DS. MyD-88 L265P mutations are present in some cases of vitreoretinal lymphoma. Retina. 2015 Apr; 35(4):624-7.
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Harberts E, Zhou H, Fishelevich R, Liu J, Gaspari AA. Ultraviolet radiation signaling through TLR4/MyD88 constrains DNA repair and plays a role in cutaneous immunosuppression. J Immunol. 2015 Apr 01; 194(7):3127-35.
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Mantegazza AR, Zajac AL, Twelvetrees A, Holzbaur EL, Amigorena S, Marks MS. TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation. Proc Natl Acad Sci U S A. 2014 Oct 28; 111(43):15508-13.
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Fernandes-Alnemri T, Kang S, Anderson C, Sagara J, Fitzgerald KA, Alnemri ES. Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome. J Immunol. 2013 Oct 15; 191(8):3995-9.