Interleukin-12 Subunit p40
"Interleukin-12 Subunit p40" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine subunit that is a component of both interleukin-12 and interleukin-23. It binds to the INTERLEUKIN-12 SUBUNIT P35 via a disulfide bond to form interleukin-12 and to INTERLEUKIN-23 SUBUNIT P19 to form interleukin-23.
| Descriptor ID |
D053762
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| MeSH Number(s) |
D12.644.276.374.465.512.500 D12.644.276.374.465.759.249 D12.776.467.374.465.512.500 D12.776.467.374.465.759.249 D23.529.374.465.512.500 D23.529.374.465.550.249
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| Concept/Terms |
Interleukin-12 Subunit p40- Interleukin-12 Subunit p40
- Interleukin 12 Subunit p40
- Interleukin-23 Subunit p40
- Interleukin 23 Subunit p40
- p40, Interleukin-23 Subunit
- Interleukin-12,23 p40 Subunit
- Interleukin 12,23 p40 Subunit
- p40 Subunit, Interleukin-12,23
- Interleukin-12b
- Interleukin 12b
- IL-12p40
- Interleukin-12 beta Chain
- Chain, Interleukin-12 beta
- Interleukin 12 beta Chain
- beta Chain, Interleukin-12
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-12 Subunit p40".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-12 Subunit p40".
This graph shows the total number of publications written about "Interleukin-12 Subunit p40" by people in this website by year, and whether "Interleukin-12 Subunit p40" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-12 Subunit p40" by people in Profiles.
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Terao C, Matsumura T, Yoshifuji H, Kirino Y, Maejima Y, Nakaoka Y, Takahashi M, Amiya E, Tamura N, Nakajima T, Origuchi T, Horita T, Matsukura M, Kochi Y, Ogimoto A, Yamamoto M, Takahashi H, Nakayamada S, Saito K, Wada Y, Narita I, Kawaguchi Y, Yamanaka H, Ohmura K, Atsumi T, Tanemoto K, Miyata T, Kuwana M, Komuro I, Tabara Y, Ueda A, Isobe M, Mimori T, Matsuda F. Takayasu arteritis and ulcerative colitis: high rate of co-occurrence and genetic overlap. Arthritis Rheumatol. 2015 May; 67(8):2226-32.
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Kasper LH, Everitt D, Leist TP, Ryan KA, Mascelli MA, Johnson K, Raychaudhuri A, Vollmer T. A phase I trial of an interleukin-12/23 monoclonal antibody in relapsing multiple sclerosis. Curr Med Res Opin. 2006 Sep; 22(9):1671-8.
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Li J, Gran B, Zhang GX, Ventura ES, Siglienti I, Rostami A, Kamoun M. Differential expression and regulation of IL-23 and IL-12 subunits and receptors in adult mouse microglia. J Neurol Sci. 2003 Nov 15; 215(1-2):95-103.
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Gran B, Zhang GX, Yu S, Li J, Chen XH, Ventura ES, Kamoun M, Rostami A. IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination. J Immunol. 2002 Dec 15; 169(12):7104-10.