Malformations of Cortical Development
"Malformations of Cortical Development" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Abnormalities in the development of the CEREBRAL CORTEX. These include malformations arising from abnormal neuronal and glial CELL PROLIFERATION or APOPTOSIS (Group I); abnormal neuronal migration (Group II); and abnormal establishment of cortical organization (Group III). Many INBORN METABOLIC BRAIN DISORDERS affecting CNS formation are often associated with cortical malformations. They are common causes of EPILEPSY and developmental delay.
Descriptor ID |
D054220
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MeSH Number(s) |
C10.500.507 C16.131.666.507
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Concept/Terms |
Malformations of Cortical Development- Malformations of Cortical Development
- Cortical Development Malformation
- Cortical Development Malformations
- Development Malformation, Cortical
- Development Malformations, Cortical
- Malformations of Cerebral Cortex Development
Cortical Dysplasia- Cortical Dysplasia
- Cortical Dysplasias
- Dysplasia, Cortical
- Dysplasias, Cortical
- Cortical Dysplasia, Cerebral
- Cerebral Cortical Dysplasias
- Cortical Dysplasias, Cerebral
- Dysplasia, Cerebral Cortical
- Dysplasias, Cerebral Cortical
- Cerebral Cortical Dysplasia
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Below are MeSH descriptors whose meaning is more general than "Malformations of Cortical Development".
Below are MeSH descriptors whose meaning is more specific than "Malformations of Cortical Development".
This graph shows the total number of publications written about "Malformations of Cortical Development" by people in this website by year, and whether "Malformations of Cortical Development" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 1 | 2 |
2009 | 1 | 0 | 1 |
2011 | 1 | 1 | 2 |
2012 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Malformations of Cortical Development" by people in Profiles.
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Li H, Nikam R, Kandula V, Chow HM, Choudhary AK. Comparison of NODDI and spherical mean signal for measuring intra-neurite volume fraction. Magn Reson Imaging. 2019 04; 57:151-155.
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Agarwal N, Krishnan B, Burgess RC, Prayson RA, Alexopoulos AV, Gupta A. Magnetoencephalographic Characteristics of Cortical Dysplasia in Children. Pediatr Neurol. 2018 01; 78:13-19.
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Rivi?re JB, Mirzaa GM, O'Roak BJ, Beddaoui M, Alcantara D, Conway RL, St-Onge J, Schwartzentruber JA, Gripp KW, Nikkel SM, Worthylake T, Sullivan CT, Ward TR, Butler HE, Kramer NA, Albrecht B, Armour CM, Armstrong L, Caluseriu O, Cytrynbaum C, Drolet BA, Innes AM, Lauzon JL, Lin AE, Mancini GM, Meschino WS, Reggin JD, Saggar AK, Lerman-Sagie T, Uyanik G, Weksberg R, Zirn B, Beaulieu CL, Majewski J, Bulman DE, O'Driscoll M, Shendure J, Graham JM, Boycott KM, Dobyns WB. De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes. Nat Genet. 2012 Jun 24; 44(8):934-40.
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Lucas MM, Lenck-Santini PP, Holmes GL, Scott RC. Impaired cognition in rats with cortical dysplasia: additional impact of early-life seizures. Brain. 2011 Jun; 134(Pt 6):1684-93.
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Saporta AS, Kumar A, Govindan RM, Sundaram SK, Chugani HT. Arcuate fasciculus and speech in congenital bilateral perisylvian syndrome. Pediatr Neurol. 2011 Apr; 44(4):270-4.
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Luat AF, Chugani HT. Congenital perisylvian dysfunction - is it a spectrum? Dev Med Child Neurol. 2010 Jan; 52(1):6-7.
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Wakamoto H, Chugani DC, Juh?sz C, Muzik O, Kupsky WJ, Chugani HT. Alpha-methyl-l-tryptophan positron emission tomography in epilepsy with cortical developmental malformations. Pediatr Neurol. 2008 Sep; 39(3):181-8.
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Juh?sz C, Asano E, Shah A, Chugani DC, Batista CE, Muzik O, Sood S, Chugani HT. Focal decreases of cortical GABAA receptor binding remote from the primary seizure focus: what do they indicate? Epilepsia. 2009 Feb; 50(2):240-50.