Phosphorothioate Oligonucleotides
"Phosphorothioate Oligonucleotides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Modified oligonucleotides in which one of the oxygens of the phosphate group is replaced with a sulfur atom.
| Descriptor ID |
D054735
|
| MeSH Number(s) |
D13.695.578.424.575
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phosphorothioate Oligonucleotides".
Below are MeSH descriptors whose meaning is more specific than "Phosphorothioate Oligonucleotides".
This graph shows the total number of publications written about "Phosphorothioate Oligonucleotides" by people in this website by year, and whether "Phosphorothioate Oligonucleotides" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphorothioate Oligonucleotides" by people in Profiles.
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Nunnari G, Schnell MJ. MicroRNA-122: a therapeutic target for hepatitis C virus (HCV) infection. Front Biosci (Schol Ed). 2011; 3:1032-7.
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Ponnappa BC, Israel Y, Aini M, Zhou F, Russ R, Cao QN, Hu Y, Rubin R. Inhibition of tumor necrosis factor alpha secretion and prevention of liver injury in ethanol-fed rats by antisense oligonucleotides. Biochem Pharmacol. 2005 Feb 15; 69(4):569-77.
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Fernandez V, Videla LA, Tapia G, Israel Y. Increases in tumor necrosis factor-alpha in response to thyroid hormone-induced liver oxidative stress in the rat. Free Radic Res. 2002 Jul; 36(7):719-25.