SOX9 Transcription Factor
"SOX9 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A SOXE transcription factor that plays a critical role in regulating CHONDROGENESIS; OSTEOGENESIS; and male sex determination. Loss of function of the SOX9 transcription factor due to genetic mutations is a cause of CAMPOMELIC DYSPLASIA.
| Descriptor ID |
D055758
|
| MeSH Number(s) |
D12.776.260.719.500.500 D12.776.660.235.400.750.500.500 D12.776.664.235.400.750.500.500 D12.776.930.823.500.500
|
| Concept/Terms |
SOX9 Transcription Factor- SOX9 Transcription Factor
- Transcription Factor, SOX9
- SOX-9 Transcription Factor
- SOX 9 Transcription Factor
- Transcription Factor, SOX-9
|
Below are MeSH descriptors whose meaning is more general than "SOX9 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "SOX9 Transcription Factor".
This graph shows the total number of publications written about "SOX9 Transcription Factor" by people in this website by year, and whether "SOX9 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2009 | 2 | 1 | 3 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "SOX9 Transcription Factor" by people in Profiles.
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Shin S, Walton G, Aoki R, Brondell K, Schug J, Fox A, Smirnova O, Dorrell C, Erker L, Chu AS, Wells RG, Grompe M, Greenbaum LE, Kaestner KH. Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential. Genes Dev. 2011 Jun 1; 25(11):1185-92.
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Cheng CC, Uchiyama Y, Hiyama A, Gajghate S, Shapiro IM, Risbud MV. PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc. J Cell Physiol. 2009 Dec; 221(3):668-76.
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Zhang Y, Markova D, Im HJ, Hu W, Thonar EJ, He TC, An HS, Phillips FM, Anderson DG. Primary bovine intervertebral disc cells transduced with adenovirus overexpressing 12 BMPs and Sox9 maintain appropriate phenotype. Am J Phys Med Rehabil. 2009 Jun; 88(6):455-63.
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Gilbert JR, Adams CS, Shapiro IM, Hickok NJ. A novel short hairpin RNA (shRNA) expression system promotes Sox9-dependent gene silencing. Plasmid. 2009 Jul; 62(1):50-5.
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Tsai TT, Guttapalli A, Oguz E, Chen LH, Vaccaro AR, Albert TJ, Shapiro IM, Risbud MV. Fibroblast growth factor-2 maintains the differentiation potential of nucleus pulposus cells in vitro: implications for cell-based transplantation therapy. Spine (Phila Pa 1976). 2007 Mar 1; 32(5):495-502.
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Piera-Velazquez S, Hawkins DF, Whitecavage MK, Colter DC, Stokes DG, Jimenez SA. Regulation of the human SOX9 promoter by Sp1 and CREB. Exp Cell Res. 2007 Apr 1; 313(6):1069-79.
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Colter DC, Piera-Velazquez S, Hawkins DF, Whitecavage MK, Jimenez SA, Stokes DG. Regulation of the human Sox9 promoter by the CCAAT-binding factor. Matrix Biol. 2005 May; 24(3):185-97.
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Zhang P, Jimenez SA, Stokes DG. Regulation of human COL9A1 gene expression. Activation of the proximal promoter region by SOX9. J Biol Chem. 2003 Jan 3; 278(1):117-23.