High-Throughput Nucleotide Sequencing

"High-Throughput Nucleotide Sequencing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc.

Descriptor ID	D059014
MeSH Number(s)	E05.393.760.319
Concept/Terms	High-Throughput Nucleotide Sequencing High-Throughput Nucleotide Sequencing High Throughput Nucleotide Sequencing Nucleotide Sequencing, High-Throughput Sequencing, High-Throughput Nucleotide Massively-Parallel Sequencing Massively-Parallel Sequencing Massively Parallel Sequencing Sequencing, Massively-Parallel Sequencings, Massively-Parallel High-Throughput RNA Sequencing High-Throughput RNA Sequencing High Throughput RNA Sequencing RNA Sequencing, High-Throughput Sequencing, High-Throughput RNA Deep Sequencing Deep Sequencing Deep Sequencings Sequencing, Deep Sequencings, Deep High-Throughput DNA Sequencing High-Throughput DNA Sequencing DNA Sequencing, High-Throughput High Throughput DNA Sequencing High-Throughput DNA Sequencings Sequencing, High-Throughput DNA

Below are MeSH descriptors whose meaning is more general than "High-Throughput Nucleotide Sequencing".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Sequence Analysis [E05.393.760]
High-Throughput Nucleotide Sequencing [E05.393.760.319]

Below are MeSH descriptors whose meaning is related to "High-Throughput Nucleotide Sequencing".

Below are MeSH descriptors whose meaning is more specific than "High-Throughput Nucleotide Sequencing".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "High-Throughput Nucleotide Sequencing" by people in this website by year, and whether "High-Throughput Nucleotide Sequencing" was a major or minor topic of these publications.

Bar chart showing 282 publications over 15 distinct years, with a maximum of 38 publications in 2016 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2011	2	0	2
2012	2	2	4
2013	3	6	9
2014	10	10	20
2015	13	12	25
2016	14	24	38
2017	10	16	26
2018	12	16	28
2019	6	28	34
2020	12	26	38
2021	9	16	25
2022	2	13	15
2023	2	5	7
2024	3	5	8
2025	0	3	3

Below are the most recent publications written about "High-Throughput Nucleotide Sequencing" by people in Profiles.

Lasota J, Kaczorowski M, Chlopek M, Milek-Krupa J, Szczepaniak M, Ylaya K, Chodyna M, Izycka-Swieszewska E, Scherping A, Czapiewski P, Dziuba I, Kato Y, Halon A, Kowalik A, Miettinen M. An immunohistochemical and molecular genetic study of 60 colorectal carcinoma brain metastases in pursuit of predictive biomarkers for cancer therapy. Hum Pathol. 2025 Jan; 155:105717.

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Ibrahim F, Mourelatos Z. Defining the True Native Ends of RNAs at Single-Molecule Level with TERA-Seq. Methods Mol Biol. 2025; 2863:359-372.

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Soni A, Beisser D, Mladenov E, H?ller M, Wohlers I, Nikolov V, Magin S, Mussfeldt T, Klein-Hitpass L, Cornforth MN, Loucas BD, Rahmann S, Iliakis G. NGS Detects Extensive Genomic Alterations in Survivors of Irradiated Normal Human Fibroblast Cells. Radiat Res. 2025 01 01; 203(1):37-52.

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Gilstrop Thompson M, Xu W, Moore B, Wang T, Sun N, Pewar H, Avent ND, Vernaza A, Acosta F, Saben JL, Souter V, Parmar S, Sengupta U, Altug Y, EmBree J, Cantos C, Kotwaliwale C, Babiarz J, Zimmermann B, Swenerton R, Meltzer JT. Clinical Validation of a Prenatal Cell-Free DNA Screening Test for Fetal RHD in a Large U.S. Cohort. Obstet Gynecol. 2025 Feb 01; 145(2):211-216.

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Tumati A, Marshall TE, Greenspun B, Chen Z, Azar SA, Keutgen XM, Laird AM, Beninato T, Zarnegar R, Fahey TJ, Finnerty BM. Evaluating the clinical performance of an updated microRNA classifier in indeterminate and RAS-mutated thyroid nodule management: A multi-institutional study. Surgery. 2025 01; 177:108833.

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Harris L, Shankar LK, Hildebrandt C, Rubinstein WS, Langlais K, Rodriguez H, Berger A, Freymann J, Huang EP, Williams PM, Zenklusen JC, Ochs R, Tezak Z, Sahiner B. Resource requirements to accelerate clinical applications of next-generation sequencing and radiomics: workshop commentary and review. J Natl Cancer Inst. 2024 Oct 01; 116(10):1562-1570.

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Kataoka K, Mori K, Nakamura Y, Watanabe J, Akazawa N, Hirata K, Yokota M, Kato K, Kotaka M, Yamazaki K, Kagawa Y, Mishima S, Ando K, Miyo M, Yukami H, Laliotis G, Sharma S, Palsuledesai CC, Rabinowitz M, Jurdi A, Liu MC, Aleshin A, Kotani D, Bando H, Taniguchi H, Takemasa I, Kato T, Yoshino T, Oki E. Survival benefit of adjuvant chemotherapy based on molecular residual disease detection in resected colorectal liver metastases: subgroup analysis from CIRCULATE-Japan GALAXY. Ann Oncol. 2024 Nov; 35(11):1015-1025.

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Volovsky M, Scott RT, Seli E. Non-invasive preimplantation genetic testing for aneuploidy: is the promise real? Hum Reprod. 2024 09 01; 39(9):1899-1908.

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Piera-Velazquez S, Fortina P, Jimenez SA. Comparison of serum exosome miRNA from patients with Raynaud's phenomenon with positive and negative serum antinuclear antibodies. Clin Exp Rheumatol. 2024 Aug; 42(8):1629-1634.

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Saeidian AH, March ME, Youssefian L, Watson DJ, Bhandari E, Wang X, Zhao X, Owen NM, Strong A, Harr MH, Bhoj E, Zackai E, Vahidnezhad H, Gudjonsson JE, Cederbaum SD, Deignan JL, Glessner J, Grody WW, Hakonarson H. Secondary ACMG and non-ACMG genetic findings in a multiethnic cohort of 16,713 pediatric participants. Genet Med. 2024 Nov; 26(11):101225.

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