"Morpholinos" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Synthetic analogs of NUCLEIC ACIDS composed of morpholine ring derivatives (MORPHOLINES) linked by phosphorodimidates. One standard DNA nucleic acid base (ADENINE; GUANINE; CYTOSINE; OR THYMINE) is bound to each morpholine ring.
Descriptor ID |
D060172
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MeSH Number(s) |
D03.383.533.640.562 D13.695.578.424.337
|
Concept/Terms |
Morpholinos- Morpholinos
- Morpholino Oligonucleotides
- Oligonucleotides, Morpholino
- Phosphorodiamidate Morpholino Oligomers
- Morpholino Oligomers, Phosphorodiamidate
- Oligomers, Phosphorodiamidate Morpholino
- PMO Oligomers
- Oligomers, PMO
- Morpholino Oligos
- Oligos, Morpholino
- MORF Oligomers
- Oligomers, MORF
|
Below are MeSH descriptors whose meaning is more general than "Morpholinos".
Below are MeSH descriptors whose meaning is more specific than "Morpholinos".
This graph shows the total number of publications written about "Morpholinos" by people in this website by year, and whether "Morpholinos" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Morpholinos" by people in Profiles.
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Lai BS, Witola WH, El Bissati K, Zhou Y, Mui E, Fomovska A, McLeod R. Molecular target validation, antimicrobial delivery, and potential treatment of Toxoplasma gondii infections. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14182-7.
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Li Q, Frank M, Akiyama M, Shimizu H, Ho SY, Thisse C, Thisse B, Sprecher E, Uitto J. Abca12-mediated lipid transport and Snap29-dependent trafficking of lamellar granules are crucial for epidermal morphogenesis in a zebrafish model of ichthyosis. Dis Model Mech. 2011 Nov; 4(6):777-85.
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Duffy KT, McAleer MF, Davidson WR, Kari L, Kari C, Liu CG, Farber SA, Cheng KC, Mest JR, Wickstrom E, Dicker AP, Rodeck U. Coordinate control of cell cycle regulatory genes in zebrafish development tested by cyclin D1 knockdown with morpholino phosphorodiamidates and hydroxyprolyl-phosphono peptide nucleic acids. Nucleic Acids Res. 2005; 33(15):4914-21.