David Goodwin

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records and Publicatio - Thomas Jefferson University
Address833 Chestnut Street
Philadelphia PA 19023
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Garthwaite G, Hampden-Smith K, Wilson GW, Goodwin DA, Garthwaite J. Nitric oxide targets oligodendrocytes and promotes their morphological differentiation. Glia. 2015 Mar; 63(3):383-99. PMID: 25327839.
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    2. Tobin GA, Zhang J, Goodwin D, Stewart S, Xu L, Knapton A, Gonz?lez C, Bancos S, Zhang L, Lawton MP, Enerson BE, Weaver JL. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicol Pathol. 2014 Jun; 42(4):709-24. PMID: 24705881.
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    3. Jones RB, Garrison KE, Mujib S, Mihajlovic V, Aidarus N, Hunter DV, Martin E, John VM, Zhan W, Faruk NF, Gyenes G, Sheppard NC, Priumboom-Brees IM, Goodwin DA, Chen L, Rieger M, Muscat-King S, Loudon PT, Stanley C, Holditch SJ, Wong JC, Clayton K, Duan E, Song H, Xu Y, SenGupta D, Tandon R, Sacha JB, Brockman MA, Benko E, Kovacs C, Nixon DF, Ostrowski MA. HERV-K-specific T cells eliminate diverse HIV-1/2 and SIV primary isolates. J Clin Invest. 2012 Dec; 122(12):4473-89. PMID: 23143309.
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    4. Sacha JB, Kim IJ, Chen L, Ullah JH, Goodwin DA, Simmons HA, Schenkman DI, von Pelchrzim F, Gifford RJ, Nimityongskul FA, Newman LP, Wildeboer S, Lappin PB, Hammond D, Castrovinci P, Piaskowski SM, Reed JS, Beheler KA, Tharmanathan T, Zhang N, Muscat-King S, Rieger M, Fernandes C, Rumpel K, Gardner JP, Gebhard DH, Janies J, Shoieb A, Pierce BG, Trajkovic D, Rakasz E, Rong S, McCluskie M, Christy C, Merson JR, Jones RB, Nixon DF, Ostrowski MA, Loudon PT, Pruimboom-Brees IM, Sheppard NC. Vaccination with cancer- and HIV infection-associated endogenous retrotransposable elements is safe and immunogenic. J Immunol. 2012 Aug 01; 189(3):1467-79. PMID: 22745376.
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    5. Garthwaite G, Bartus K, Malcolm D, Goodwin D, Kollb-Sielecka M, Kollb-Sielecka M, Dooldeniya C, Garthwaite J. Signaling from blood vessels to CNS axons through nitric oxide. J Neurosci. 2006 Jul 19; 26(29):7730-40. PMID: 16855101.
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    6. Garthwaite G, Batchelor AM, Goodwin DA, Hewson AK, Leeming K, Ahmed Z, Cuzner ML, Garthwaite J. Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis. Eur J Neurosci. 2005 Apr; 21(8):2127-35. PMID: 15869509.
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    7. Griffiths C, Garthwaite G, Goodwin DA, Garthwaite J. Dynamics of nitric oxide during simulated ischaemia-reperfusion in rat striatal slices measured using an intrinsic biosensor, soluble guanylyl cyclase. Eur J Neurosci. 2002 Mar; 15(6):962-8. PMID: 11918655.
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    8. Garthwaite G, Goodwin DA, Neale S, Riddall D, Garthwaite J. Soluble guanylyl cyclase activator YC-1 protects white matter axons from nitric oxide toxicity and metabolic stress, probably through Na(+) channel inhibition. Mol Pharmacol. 2002 Jan; 61(1):97-104. PMID: 11752210.
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    9. Garthwaite G, Goodwin DA, Batchelor AM, Leeming K, Garthwaite J. Nitric oxide toxicity in CNS white matter: an in vitro study using rat optic nerve. Neuroscience. 2002; 109(1):145-55. PMID: 11784706.
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    10. Alber DG, Powell KL, Vallance P, Goodwin DA, Grahame-Clarke C. Herpesvirus infection accelerates atherosclerosis in the apolipoprotein E-deficient mouse. Circulation. 2000 Aug 15; 102(7):779-85. PMID: 10942747.
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    11. Bellamy TC, Wood J, Goodwin DA, Garthwaite J. Rapid desensitization of the nitric oxide receptor, soluble guanylyl cyclase, underlies diversity of cellular cGMP responses. Proc Natl Acad Sci U S A. 2000 Mar 14; 97(6):2928-33. PMID: 10717006.
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    12. Garthwaite G, Goodwin DA, Garthwaite J. Nitric oxide stimulates cGMP formation in rat optic nerve axons, providing a specific marker of axon viability. Eur J Neurosci. 1999 Dec; 11(12):4367-72. PMID: 10594663.
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    13. Garthwaite G, Brown G, Batchelor AM, Goodwin DA, Garthwaite J. Mechanisms of ischaemic damage to central white matter axons: a quantitative histological analysis using rat optic nerve. Neuroscience. 1999; 94(4):1219-30. PMID: 10625062.
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