"Acetate-CoA Ligase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of CoA derivatives from ATP, acetate, and CoA to form AMP, pyrophosphate, and acetyl CoA. It acts also on propionates and acrylates. EC 6.2.1.1.
| Descriptor ID |
D000106
|
| MeSH Number(s) |
D08.811.464.267.500.200
|
| Concept/Terms |
Acetate-CoA Ligase- Acetate-CoA Ligase
- Acetate CoA Ligase
- Ligase, Acetate-CoA
- Acetyl CoA Synthetase
- CoA Synthetase, Acetyl
- Synthetase, Acetyl CoA
- Acetyl Activating Enzyme
- Activating Enzyme, Acetyl
- Enzyme, Acetyl Activating
- Acetyl Coenzyme A Synthetase
- Acetate Thiokinase
- Thiokinase, Acetate
- Acetothiokinase
|
Below are MeSH descriptors whose meaning is more general than "Acetate-CoA Ligase".
Below are MeSH descriptors whose meaning is more specific than "Acetate-CoA Ligase".
This graph shows the total number of publications written about "Acetate-CoA Ligase" by people in this website by year, and whether "Acetate-CoA Ligase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 2 | 0 | 2 |
| 2004 | 2 | 0 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acetate-CoA Ligase" by people in Profiles.
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Dougherty WG, Rangan K, O'Hagan MJ, Yap GP, Riordan CG. Binuclear complexes containing a methylnickel moiety: relevance to organonickel intermediates in acetyl coenzyme A synthase catalysis. J Am Chem Soc. 2008 Oct 15; 130(41):13510-1.
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Eckert NA, Dougherty WG, Yap GP, Riordan CG. Methyl transfer from methylcobaloxime to (triphos)Ni(PPh(3)): relevance to the mechanism of acetyl coenzyme A synthase. J Am Chem Soc. 2007 Aug 1; 129(30):9286-7.
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Ingram-Smith C, Woods BI, Smith KS. Characterization of the acyl substrate binding pocket of acetyl-CoA synthetase. Biochemistry. 2006 Sep 26; 45(38):11482-90.
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Schenker R, Mock MT, Kieber-Emmons MT, Riordan CG, Brunold TC. Spectroscopic and computational studies on [Ni(tmc)CH3]OTf: implications for Ni-methyl bonding in the A cluster of acetyl-CoA synthase. Inorg Chem. 2005 May 16; 44(10):3605-17.
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Riordan CG. Synthetic chemistry and chemical precedents for understanding the structure and function of acetyl coenzyme A synthase. J Biol Inorg Chem. 2004 Jul; 9(5):542-9.
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Krishnan R, Riordan CG. Cys-Gly-Cys tripeptide complexes of nickel: binuclear analogues for the catalytic site in acetyl coenzyme a synthase. J Am Chem Soc. 2004 Apr 14; 126(14):4484-5.
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Krishnan R, Voo JK, Riordan CG, Zahkarov L, Rheingold AL. Thiolate-bridged nickel-copper complexes: a binuclear model for the catalytic site of acetyl coenzyme a synthase? J Am Chem Soc. 2003 Apr 16; 125(15):4422-3.
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Craft JL, Mandimutsira BS, Fujita K, Riordan CG, Brunold TC. Spectroscopic and computational studies of a Ni(+)-CO model complex: implications for the acetyl-CoA synthase catalytic mechanism. Inorg Chem. 2003 Feb 10; 42(3):859-67.