Acute-Phase Proteins

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"Acute-Phase Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins that are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. These proteins can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumor markers.

Descriptor ID	D000209
MeSH Number(s)	D12.776.124.050
Concept/Terms	Acute-Phase Proteins Acute-Phase Proteins Acute Phase Proteins Proteins, Acute-Phase Proteins, Acute Phase Reactants, Acute-Phase Reactants, Acute Phase Acute-Phase Reactants Acute Phase Reactants Acute-Phase Protein Acute Phase Protein Protein, Acute-Phase Acute-Phase Glycoproteins Acute-Phase Glycoproteins Acute Phase Glycoproteins Glycoproteins, Acute-Phase

Below are MeSH descriptors whose meaning is more general than "Acute-Phase Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Acute-Phase Proteins [D12.776.124.050]

Below are MeSH descriptors whose meaning is related to "Acute-Phase Proteins".

Below are MeSH descriptors whose meaning is more specific than "Acute-Phase Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Acute-Phase Proteins" by people in this website by year, and whether "Acute-Phase Proteins" was a major or minor topic of these publications.

Bar chart showing 22 publications over 15 distinct years, with a maximum of 4 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2000	1	0	1
2001	0	1	1
2002	1	0	1
2003	0	1	1
2004	0	1	1
2005	1	0	1
2009	1	3	4
2010	0	1	1
2011	1	1	2
2012	1	2	3
2014	1	1	2
2020	0	1	1
2022	0	1	1
2023	0	1	1

Below are the most recent publications written about "Acute-Phase Proteins" by people in Profiles.

Robinson TP, Hamidi T, Counts B, Guttridge DC, Ostrowski MC, Zimmers TA, Koniaris LG. The impact of inflammation and acute phase activation in cancer cachexia. Front Immunol. 2023; 14:1207746.

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Katz-Greenberg G, Malinchoc M, Broyles DL, Oxman D, Hamrahian SM, Maarouf OH. Urinary Neutrophil Gelatinase-Associated Lipocalin Predicts Intensive Care Unit Admission Diagnosis: A Prospective Cohort Study. Kidney360. 2022 09 29; 3(9):1502-1510.

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Palangmonthip W, Wu R, Tarima S, Bobholz SA, LaViolette PS, Gallan AJ, Iczkowski KA. Corpora amylacea in benign prostatic acini are associated with concurrent, predominantly low-grade cancer. Prostate. 2020 06; 80(9):687-697.

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Deirmengian C, Kardos K, Kilmartin P, Cameron A, Schiller K, Parvizi J. Diagnosing periprosthetic joint infection: has the era of the biomarker arrived? Clin Orthop Relat Res. 2014 Nov; 472(11):3254-62.

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Liu KD, Yang W, Go AS, Anderson AH, Feldman HI, Fischer MJ, He J, Kallem RR, Kusek JW, Master SR, Miller ER, Rosas SE, Steigerwalt S, Tao K, Weir MR, Hsu CY. Urine neutrophil gelatinase-associated lipocalin and risk of cardiovascular disease and death in CKD: results from the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2015 Feb; 65(2):267-74.

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Sung H, Choi JY, Lee SA, Lee KM, Han S, Jeon S, Song M, Lee Y, Park SK, Yoo KY, Noh DY, Ahn SH, Kang D. The association between the preoperative serum levels of lipocalin-2 and matrix metalloproteinase-9 (MMP-9) and prognosis of breast cancer. BMC Cancer. 2012 May 28; 12:193.

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Zhou F, Ciric B, Li H, Yan Y, Li K, Cullimore M, Lauretti E, Gonnella P, Zhang GX, Rostami A. IL-10 deficiency blocks the ability of LPS to regulate expression of tolerance-related molecules on dendritic cells. Eur J Immunol. 2012 Jun; 42(6):1449-58.

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Schinstock CA, Semret MH, Wagner SJ, Borland TM, Bryant SC, Kashani KB, Larson TS, Lieske JC. Urinalysis is more specific and urinary neutrophil gelatinase-associated lipocalin is more sensitive for early detection of acute kidney injury. Nephrol Dial Transplant. 2013 May; 28(5):1175-85.

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Shaw AD, Chalfin DB, Kleintjens J. The economic impact and cost-effectiveness of urinary neutrophil gelatinase-associated lipocalin after cardiac surgery. Clin Ther. 2011 Nov; 33(11):1713-25.

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Hall IE, Coca SG, Perazella MA, Eko UU, Luciano RL, Peter PR, Han WK, Parikh CR. Risk of poor outcomes with novel and traditional biomarkers at clinical AKI diagnosis. Clin J Am Soc Nephrol. 2011 Dec; 6(12):2740-9.

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