"Anesthetics, Local" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
| Descriptor ID |
D000779
|
| MeSH Number(s) |
D27.505.696.277.100.200 D27.505.696.663.850.025 D27.505.954.427.210.100.200
|
| Concept/Terms |
Anesthetics, Local- Anesthetics, Local
- Local Anesthetics
- Conduction-Blocking Anesthetics
- Conduction Blocking Anesthetics
- Anesthetics, Conduction-Blocking
- Anesthetics, Conduction Blocking
|
Below are MeSH descriptors whose meaning is more general than "Anesthetics, Local".
Below are MeSH descriptors whose meaning is more specific than "Anesthetics, Local".
This graph shows the total number of publications written about "Anesthetics, Local" by people in this website by year, and whether "Anesthetics, Local" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 1 | 4 |
| 1997 | 3 | 0 | 3 |
| 1998 | 2 | 3 | 5 |
| 1999 | 2 | 1 | 3 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 3 | 1 | 4 |
| 2003 | 2 | 1 | 3 |
| 2004 | 1 | 2 | 3 |
| 2005 | 7 | 1 | 8 |
| 2006 | 2 | 0 | 2 |
| 2007 | 2 | 3 | 5 |
| 2008 | 5 | 2 | 7 |
| 2009 | 2 | 4 | 6 |
| 2010 | 4 | 4 | 8 |
| 2011 | 2 | 2 | 4 |
| 2012 | 2 | 2 | 4 |
| 2013 | 2 | 3 | 5 |
| 2014 | 10 | 2 | 12 |
| 2015 | 6 | 2 | 8 |
| 2016 | 3 | 5 | 8 |
| 2017 | 8 | 2 | 10 |
| 2018 | 8 | 4 | 12 |
| 2019 | 5 | 3 | 8 |
| 2020 | 4 | 7 | 11 |
| 2021 | 2 | 6 | 8 |
| 2022 | 2 | 3 | 5 |
| 2023 | 0 | 7 | 7 |
| 2024 | 1 | 4 | 5 |
| 2025 | 2 | 1 | 3 |
To return to the timeline,
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Below are the most recent publications written about "Anesthetics, Local" by people in Profiles.
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Bungart B, Joudeh L, Schwenk ES, Chiang C, Fettiplace MR. Comparative Methods to Predict Redosing of Bupivacaine and Ropivacaine in Truncal Catheters. Anesthesiology. 2025 May 01; 142(5):885-895.
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Bakillah E, Brooks AD, Adekeye S. Switching to Tumescent Dissection in Mastectomy. Breast J. 2025; 2025:7634729.
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Fares MY, Daher M, Boufadel P, Khan AZ, Abboud JA. The Use of Liposomal Bupivacaine for Pain Control After Shoulder Surgery: A Systematic Review and Meta-analysis. Am J Sports Med. 2025 Apr; 53(5):1254-1263.
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Kasper AA, Plusch K, Voskerijian A, Barnabei D, Rivlin M, Beredjiklian PK, Wang ML. Efficacy of Direct Versus Peripheral Adjuvant Dexamethasone on Duration and Rebound Pain in Regional Anesthesia for Outpatient Distal Radius Fracture Fixation: A Prospective Randomized Controlled Blinded Study. Hand (N Y). 2025 Oct; 20(7):1132-1137.
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Ng A, Lou J, Wang D. Potential S1 Nerve Root Blocks Associated with Sacroiliac Joint Injections. Pain Res Manag. 2024; 2024:8064804.
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Pederiva D, Pilla F, Chiaramonte I, Rinaldi A, Rossomando V, Brunello M, Vita F, Faldini C. Under 2$ hand anesthesia? Our first 800 cases with Wide-Awake Local Anesthesia No Tourniquet (WALANT) in hand surgery. Musculoskelet Surg. 2025 Jun; 109(2):163-166.
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Sun G, Atary J, Raju AV, Pozek JJ, Schwenk ES. Sometimes less is more when it comes to peripheral nerve blocks. J Clin Anesth. 2024 06; 94:111376.
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Harrer S, Yayac M, Toci GR, Levicoff E, Courtney PM, Star AM, Saxena A. Efficacy of Liposomal Bupivacaine Versus a Traditional Local Anesthetic in Periarticular Injections during Total Hip Arthroplasty: A Systematic Review and Meta-analysis. J Surg Orthop Adv. 2024; 33(3):143-151.
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Weaver HL, Carbaugh CM, Madejczyk MS, Raiciulescu S, Martin ML, Widder MW. Comparison of Tricaine Methanesulfonate (MS-222) and Alfaxalone Anesthesia in Zebrafish (Danio rerio). J Am Assoc Lab Anim Sci. 2024 01 01; 63(1):74-80.
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Mirsch D, Jelic T, Prats MI, Dreyfuss A, Yates E, Kummer T, Stenberg B, Vlasica K, Nagdev A. Just the facts: brachial plexus blocks for upper extremity injuries in the emergency department. CJEM. 2024 04; 26(4):228-231.